Show simple item record

dc.contributor.authorMajidi, S
dc.contributor.authorFifi, JT
dc.contributor.authorLadner, TR
dc.contributor.authorLara-Reyna, J
dc.contributor.authorYaeger, KA
dc.contributor.authorYim, B
dc.contributor.authorDangayach, N
dc.contributor.authorOxley, TJ
dc.contributor.authorShigematsu, T
dc.contributor.authorKummer, BR
dc.contributor.authorStein, LK
dc.contributor.authorWeinberger, J
dc.contributor.authorFara, MG
dc.contributor.authorDe Leacy, R
dc.contributor.authorDhamoon, MS
dc.contributor.authorTuhrim, S
dc.contributor.authorMocco, J
dc.identifier.citationMajidi, S., Fifi, J. T., Ladner, T. R., Lara-Reyna, J., Yaeger, K. A., Yim, B., Dangayach, N., Oxley, T. J., Shigematsu, T., Kummer, B. R., Stein, L. K., Weinberger, J., Fara, M. G., De Leacy, R., Dhamoon, M. S., Tuhrim, S. & Mocco, J. (2020). Emergent Large Vessel Occlusion Stroke During New York City's COVID-19 Outbreak: Clinical Characteristics and Paraclinical Findings.. Stroke, 51 (9), pp.2656-2663.
dc.description.abstractBackground and Purpose: The 2019 novel coronavirus outbreak and its associated disease (coronavirus disease 2019 [COVID-19]) have created a worldwide pandemic. Early data suggest higher rate of ischemic stroke in severe COVID-19 infection. We evaluated whether a relationship exists between emergent large vessel occlusion (ELVO) and the ongoing COVID-19 outbreak. Methods: This is a retrospective, observational case series. Data were collected from all patients who presented with ELVO to the Mount Sinai Health System Hospitals across New York City during the peak 3 weeks of hospitalization and death from COVID-19. Patients’ demographic, comorbid conditions, cardiovascular risk factors, COVID-19 disease status, and clinical presentation were extracted from the electronic medical record. Comparison was made between COVID-19 positive and negative cohorts. The incidence of ELVO stroke was compared with the pre-COVID period. Results: Forty-five consecutive ELVO patients presented during the observation period. Fifty-three percent of patients tested positive for COVID-19. Total patients’ mean (±SD) age was 66 (±17). Patients with COVID-19 were significantly younger than patients without COVID-19, 59±13 versus 74±17 (odds ratio [95% CI], 0.94 [0.81–0.98]; P=0.004). Seventy-five percent of patients with COVID-19 were male compared with 43% of patients without COVID-19 (odds ratio [95% CI], 3.99 [1.12–14.17]; P=0.032). Patients with COVID-19 were less likely to be White (8% versus 38% [odds ratio (95% CI), 0.15 (0.04–0.81); P=0.027]). In comparison to a similar time duration before the COVID-19 outbreak, a 2-fold increase in the total number of ELVO was observed (estimate: 0.78 [95% CI, 0.47–1.08], P≤0.0001). Conclusions: More than half of the ELVO stroke patients during the peak time of the New York City’s COVID-19 outbreak were COVID-19 positive, and those patients with COVID-19 were younger, more likely to be male, and less likely to be White. Our findings also suggest an increase in the incidence of ELVO stroke during the peak of the COVID-19 outbreak.
dc.publisherAmerican Heart Association
dc.titleEmergent Large Vessel Occlusion Stroke During New York City's COVID-19 Outbreak: Clinical Characteristics and Paraclinical Findings.
dc.typeJournal Article
melbourne.affiliation.departmentMedicine (RMH)
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.openaccess.statusPublished version
melbourne.contributor.authorOxley, Thomas
melbourne.accessrightsAccess this item via the Open Access location

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record