Correlations between COVID-19 and burden of dementia: An ecological study and review of literature

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    Author
    Azarpazhooha, MR; Amiri, A; Morovatdar, N; Steinwender, S; Ardani, AR; Yassi, N; Biller, J; Stranges, S; Belasi, MT; Neya, SK; ...
    Date
    2020-09-15
    Source Title
    Journal of the Neurological Sciences
    Publisher
    ELSEVIER
    University of Melbourne Author/s
    Yassi, Nawaf
    Affiliation
    Medicine and Radiology
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    Document Type
    Journal Article
    Citations
    Azarpazhooha, M. R., Amiri, A., Morovatdar, N., Steinwender, S., Ardani, A. R., Yassi, N., Biller, J., Stranges, S., Belasi, M. T., Neya, S. K., Khorram, B., Andalibi, M. S. S., Arsang-Jang, S., Mokhber, N. & Di Napoli, M. (2020). Correlations between COVID-19 and burden of dementia: An ecological study and review of literature. JOURNAL OF THE NEUROLOGICAL SCIENCES, 416, https://doi.org/10.1016/j.jns.2020.117013.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/254592
    DOI
    10.1016/j.jns.2020.117013
    Open Access URL
    Published version
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334961
    Abstract
    INTRODUCTION: Current evidence on the association between COVID-19 and dementia is sparse. This study aims to investigate the associations between COVID-19 caseload and the burden of dementia. METHODS: We gathered data regarding burden of dementia (disability-adjusted life years [DALYs] per 100,000), life expectancy, and healthy life expectancy (HALE) from the Global Burden of Disease (GBD) 2017 study. We obtained COVID-19 data from Our World in Data database. We analyzed the association of COVID-19 cases and deaths with the burden of dementia using Spearman's rank correlation coefficient. RESULTS: Globally, we found significant positive (p < .001) correlations between life expectancy (r = 0.60), HALE (r = 0.58), and dementia DALYs (r = 0.46) with COVID-19 caseloads. Likewise, we found similar correlations between life expectancy (r = 0.60), HALE (r = 0.58) and dementia DALYs (r = 0.54) with COVID-19 mortality. CONCLUSION: Health policymakers should clarify a targeted model of disease surveillance in order to reduce the dual burden of dementia and COVID-19.

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