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dc.contributor.authorMinlikeeva, AN
dc.contributor.authorFreudenheim, JL
dc.contributor.authorCannioto, RA
dc.contributor.authorEng, KH
dc.contributor.authorSzender, JB
dc.contributor.authorMayor, P
dc.contributor.authorEtter, JL
dc.contributor.authorCramer, DW
dc.contributor.authorDiergaarde, B
dc.contributor.authorDoherty, JA
dc.contributor.authorDörk, T
dc.contributor.authorEdwards, R
dc.contributor.authordeFazio, A
dc.contributor.authorFriel, G
dc.contributor.authorGoodman, MT
dc.contributor.authorHillemanns, P
dc.contributor.authorHøgdall, E
dc.contributor.authorJensen, A
dc.contributor.authorJordan, SJ
dc.contributor.authorKarlan, BY
dc.contributor.authorKjær, SK
dc.contributor.authorKlapdor, R
dc.contributor.authorMatsuo, K
dc.contributor.authorMizuno, M
dc.contributor.authorNagle, CM
dc.contributor.authorOdunsi, K
dc.contributor.authorPaddock, L
dc.contributor.authorRossing, MA
dc.contributor.authorSchildkraut, JM
dc.contributor.authorSchmalfeldt, B
dc.contributor.authorSegal, BH
dc.contributor.authorStarbuck, K
dc.contributor.authorTerry, KL
dc.contributor.authorWebb, PM
dc.contributor.authorZsiros, E
dc.contributor.authorNess, RB
dc.contributor.authorModugno, F
dc.contributor.authorBandera, EV
dc.contributor.authorChang-Claude, J
dc.contributor.authorMoysich, KB
dc.date.accessioned2020-12-17T03:24:41Z
dc.date.available2020-12-17T03:24:41Z
dc.date.issued2017-09-26
dc.identifierpii: bjc2017267
dc.identifier.citationMinlikeeva, A. N., Freudenheim, J. L., Cannioto, R. A., Eng, K. H., Szender, J. B., Mayor, P., Etter, J. L., Cramer, D. W., Diergaarde, B., Doherty, J. A., Dörk, T., Edwards, R., deFazio, A., Friel, G., Goodman, M. T., Hillemanns, P., Høgdall, E., Jensen, A., Jordan, S. J. ,... Moysich, K. B. (2017). History of thyroid disease and survival of ovarian cancer patients: results from the Ovarian Cancer Association Consortium, a brief report.. Br J Cancer, 117 (7), pp.1063-1069. https://doi.org/10.1038/bjc.2017.267.
dc.identifier.issn0007-0920
dc.identifier.urihttp://hdl.handle.net/11343/254874
dc.description.abstractBACKGROUND: Findings from in vitro studies suggest that increased exposure to thyroid hormones can influence progression of ovarian tumours. However, epidemiologic evidence on this topic is limited. METHODS: We pooled data from 11 studies from the Ovarian Cancer Association Consortium. Using multivariate Cox proportional hazards models, we estimated associations between hyper- and hypothyroidism and medications prescribed for these conditions with 5-year all-cause survival among women diagnosed with invasive ovarian cancer. RESULTS: Overall, there was a nonsignificant association with history of hyperthyroidism (n=160 cases) and mortality (HR=1.22; 95% CI=0.97-1.53). Furthermore, diagnosis of hyperthyroidism within the 5 years before ovarian cancer diagnosis was associated with an increased risk of death (HR=1.94; 95% CI=1.19-3.18). A more modest association was observed with history of hypothyroidism (n=624 cases) and mortality (HR=1.16; 95% CI=1.03-1.31). Neither duration of hypothyroidism nor use of thyroid medications was associated with survival. CONCLUSIONS: In this large study of women with ovarian cancer, we found that recent history of hyperthyroidism and overall history of hypothyroidism were associated with worse 5-year survival.
dc.languageeng
dc.publisherSpringer Science and Business Media LLC
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0
dc.titleHistory of thyroid disease and survival of ovarian cancer patients: results from the Ovarian Cancer Association Consortium, a brief report.
dc.typeJournal Article
dc.identifier.doi10.1038/bjc.2017.267
melbourne.affiliation.departmentMelbourne School of Population and Global Health
melbourne.source.titleBritish Journal of Cancer
melbourne.source.volume117
melbourne.source.issue7
melbourne.source.pages1063-1069
melbourne.identifier.nhmrc400281
dc.rights.licenseCC BY-NC-SA
melbourne.elementsid1324041
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625672
melbourne.contributor.authorBaglietto, Laura
dc.identifier.eissn1532-1827
melbourne.identifier.fundernameidNHMRC, 400281
melbourne.accessrightsOpen Access


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