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dc.contributor.authorWojtas, DH
dc.contributor.authorAyyer, K
dc.contributor.authorLiang, M
dc.contributor.authorMossou, E
dc.contributor.authorRomoli, F
dc.contributor.authorSeuring, C
dc.contributor.authorBeyerlein, KR
dc.contributor.authorBean, RJ
dc.contributor.authorMorgan, AJ
dc.contributor.authorOberthuer, D
dc.contributor.authorFleckenstein, H
dc.contributor.authorHeymann, M
dc.contributor.authorGati, C
dc.contributor.authorYefanov, O
dc.contributor.authorBarthelmess, M
dc.contributor.authorOrnithopoulou, E
dc.contributor.authorGalli, L
dc.contributor.authorXavier, PL
dc.contributor.authorLing, WL
dc.contributor.authorFrank, M
dc.contributor.authorYoon, CH
dc.contributor.authorWhite, TA
dc.contributor.authorBajt, S
dc.contributor.authorMitraki, A
dc.contributor.authorBoutet, S
dc.contributor.authorAquila, A
dc.contributor.authorBarty, A
dc.contributor.authorForsyth, VT
dc.contributor.authorChapman, HN
dc.contributor.authorMillane, RP
dc.date.accessioned2020-12-17T03:26:55Z
dc.date.available2020-12-17T03:26:55Z
dc.date.issued2017-11-01
dc.identifierpii: sp5001
dc.identifier.citationWojtas, D. H., Ayyer, K., Liang, M., Mossou, E., Romoli, F., Seuring, C., Beyerlein, K. R., Bean, R. J., Morgan, A. J., Oberthuer, D., Fleckenstein, H., Heymann, M., Gati, C., Yefanov, O., Barthelmess, M., Ornithopoulou, E., Galli, L., Xavier, P. L., Ling, W. L. ,... Millane, R. P. (2017). Analysis of XFEL serial diffraction data from individual crystalline fibrils. IUCRJ, 4 (Pt 6), pp.795-811. https://doi.org/10.1107/S2052252517014324.
dc.identifier.issn2052-2525
dc.identifier.urihttp://hdl.handle.net/11343/254890
dc.description.abstractSerial diffraction data collected at the Linac Coherent Light Source from crystalline amyloid fibrils delivered in a liquid jet show that the fibrils are well oriented in the jet. At low fibril concentrations, diffraction patterns are recorded from single fibrils; these patterns are weak and contain only a few reflections. Methods are developed for determining the orientation of patterns in reciprocal space and merging them in three dimensions. This allows the individual structure amplitudes to be calculated, thus overcoming the limitations of orientation and cylindrical averaging in conventional fibre diffraction analysis. The advantages of this technique should allow structural studies of fibrous systems in biology that are inaccessible using existing techniques.
dc.languageEnglish
dc.publisherINT UNION CRYSTALLOGRAPHY
dc.titleAnalysis of XFEL serial diffraction data from individual crystalline fibrils
dc.typeJournal Article
dc.identifier.doi10.1107/S2052252517014324
melbourne.affiliation.departmentSchool of Physics
melbourne.source.titleIUCrJ
melbourne.source.volume4
melbourne.source.issuePt 6
melbourne.source.pages795-811
dc.rights.licenseCC BY
melbourne.elementsid1326198
melbourne.contributor.authorMorgan, Andrew
dc.identifier.eissn2052-2525
melbourne.accessrightsOpen Access


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