The Characterisation of Pluripotent and Multipotent Stem Cells Using Fourier Transform Infrared Microspectroscopy
AuthorCao, J; Ng, ES; McNaughton, D; Stanley, EG; Elefanty, AG; Tobin, MJ; Heraud, P
Source TitleInternational Journal of Molecular Sciences
Document TypeJournal Article
CitationsCao, J., Ng, E. S., McNaughton, D., Stanley, E. G., Elefanty, A. G., Tobin, M. J. & Heraud, P. (2013). The Characterisation of Pluripotent and Multipotent Stem Cells Using Fourier Transform Infrared Microspectroscopy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14 (9), pp.17453-17476. https://doi.org/10.3390/ijms140917453.
Access StatusOpen Access
Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.
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