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dc.contributor.authorBaker, S
dc.contributor.authorThomson, N
dc.contributor.authorWeill, F-X
dc.contributor.authorHolt, KE
dc.date.accessioned2020-12-17T03:48:26Z
dc.date.available2020-12-17T03:48:26Z
dc.date.issued2018-05-18
dc.identifierpii: 360/6390/733
dc.identifier.citationBaker, S., Thomson, N., Weill, F. -X. & Holt, K. E. (2018). Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens. SCIENCE, 360 (6390), pp.733-738. https://doi.org/10.1126/science.aar3777.
dc.identifier.issn0036-8075
dc.identifier.urihttp://hdl.handle.net/11343/255039
dc.description.abstractWhole-genome sequencing (WGS) has been vital for revealing the rapid temporal and spatial evolution of antimicrobial resistance (AMR) in bacterial pathogens. Some antimicrobial-resistant pathogens have outpaced us, with untreatable infections appearing in hospitals and the community. However, WGS has additionally provided us with enough knowledge to initiate countermeasures. Although we cannot stop bacterial adaptation, the predictability of many evolutionary processes in AMR bacteria offers us an opportunity to channel them using new control strategies. Furthermore, by using WGS for coordinating surveillance and to create a more fundamental understanding of the outcome of antimicrobial treatment and AMR mechanisms, we can use current and future antimicrobials more effectively and aim to extend their longevity.
dc.languageEnglish
dc.publisherAMER ASSOC ADVANCEMENT SCIENCE
dc.titleGenomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens
dc.typeJournal Article
dc.identifier.doi10.1126/science.aar3777
melbourne.affiliation.departmentBiochemistry and Molecular Biology
melbourne.source.titleScience
melbourne.source.volume360
melbourne.source.issue6390
melbourne.source.pages733-738
dc.rights.licenseCC BY
melbourne.elementsid1330773
melbourne.contributor.authorHolt, Kathryn
dc.identifier.eissn1095-9203
melbourne.accessrightsOpen Access


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