University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Paediatrics (RCH)
  • Paediatrics (RCH) - Research Publications
  • View Item
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Paediatrics (RCH)
  • Paediatrics (RCH) - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    Ethical considerations in presymptomatic testing for variant CJD

    Thumbnail
    Citations
    Scopus
    Web of Science
    Altmetric
    14
    10
    Author
    Duncan, RE; Delatycki, MB; Collins, SJ; Boyd, A; Masters, CL; Savulescu, J
    Date
    2005-11-01
    Source Title
    JOURNAL OF MEDICAL ETHICS
    Publisher
    BMJ PUBLISHING GROUP
    University of Melbourne Author/s
    DUNCAN, RONY EMILY; Delatycki, Martin; Collins, Steven; BOYD, ALISON; Masters, Colin; Savulescu, Julian
    Affiliation
    Paediatrics Royal Children'S Hospital
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Duncan, R. E., Delatycki, M. B., Collins, S. J., Boyd, A., Masters, C. L. & Savulescu, J. (2005). Ethical considerations in presymptomatic testing for variant CJD. JOURNAL OF MEDICAL ETHICS, 31 (11), pp.625-630. https://doi.org/10.1136/jme.2005.011965.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/25526
    DOI
    10.1136/jme.2005.011965
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1734042
    Description

    C1 - Journal Articles Refereed

    Abstract
    Variant Creutzfeldt-Jakob disease (vCJD) is a fatal, transmissible, neurodegenerative disorder for which there is currently no effective treatment. vCJD arose from the zoonotic spread of bovine spongiform encephalopathy. There is now compelling evidence for human to human transmission through blood transfusions from presymptomatic carriers and experts are warning that the real epidemic may be yet to come. Imperatives exist for the development of reliable, non-invasive presymptomatic diagnostic tests. Research into such tests is well advanced. In this article the ethical implications of the availability of these tests are elaborated and comparisons drawn with predictive genetic testing for Huntington's disease and screening for HIV. Paramount to considerations is the issue of whom to test, weighing up respect for personal autonomy against obligations to benefit and protect society. A paradigm is proposed similar to that used for HIV screening but with unique features: compulsory testing of all blood/organ donors and individuals undergoing surgery or invasive procedures who have a significant risk of disease transmission.
    Keywords
    Central Nervous System ; Infectious Diseases

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [53102]
    • Paediatrics (RCH) - Research Publications [2391]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors