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dc.contributor.authorRogers, GB
dc.contributor.authorKozlowska, J
dc.contributor.authorKeeble, J
dc.contributor.authorMetcalfe, K
dc.contributor.authorFao, M
dc.contributor.authorDowd, SE
dc.contributor.authorMason, AJ
dc.contributor.authorMcGuckin, MA
dc.contributor.authorBruce, KD
dc.date.accessioned2020-12-18T02:56:21Z
dc.date.available2020-12-18T02:56:21Z
dc.date.issued2014-06-25
dc.identifierpii: srep05437
dc.identifier.citationRogers, G. B., Kozlowska, J., Keeble, J., Metcalfe, K., Fao, M., Dowd, S. E., Mason, A. J., McGuckin, M. A. & Bruce, K. D. (2014). Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice. SCIENTIFIC REPORTS, 4 (1), https://doi.org/10.1038/srep05437.
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/11343/255563
dc.description.abstractDespite the fundamental contribution of the gut microbiota to host physiology, the extent of its variation in genetically-identical animals used in research is not known. We report significant divergence in both the composition and metabolism of gut microbiota in genetically-identical adult C57BL/6 mice housed in separate controlled units within a single commercial production facility. The reported divergence in gut microbiota has the potential to confound experimental studies using mammalian models.
dc.languageEnglish
dc.publisherNATURE PUBLISHING GROUP
dc.titleFunctional divergence in gastrointestinal microbiota in physically-separated genetically identical mice
dc.typeJournal Article
dc.identifier.doi10.1038/srep05437
melbourne.affiliation.departmentMedicine Dentistry & Health Sciences
melbourne.source.titleScientific Reports
melbourne.source.volume4
melbourne.source.issue1
dc.rights.licenseCC BY-NC-ND
melbourne.elementsid1291003
melbourne.contributor.authorMcGuckin, Michael
dc.identifier.eissn2045-2322
melbourne.accessrightsOpen Access


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