University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Pharmacology and Therapeutics
  • Pharmacology and Therapeutics - Research Publications
  • View Item
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Pharmacology and Therapeutics
  • Pharmacology and Therapeutics - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    Purinergic mechanosensory transduction and visceral pain

    Thumbnail
    Download
    Published version (1.532Mb)

    Citations
    Scopus
    Web of Science
    Altmetric
    92
    75
    Author
    Burnstock, G
    Date
    2009-11-30
    Source Title
    Molecular Pain
    Publisher
    SAGE PUBLICATIONS INC
    University of Melbourne Author/s
    Burnstock, Geoffrey
    Affiliation
    Pharmacology and Therapeutics
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Burnstock, G. (2009). Purinergic mechanosensory transduction and visceral pain. MOLECULAR PAIN, 5, https://doi.org/10.1186/1744-8069-5-69.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/255697
    DOI
    10.1186/1744-8069-5-69
    Abstract
    In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain. Experimental evidence for this mechanism in urinary bladder, ureter, gut, lung, uterus, tooth-pulp and tongue is reviewed. Potential therapeutic strategies are considered for the treatment of visceral pain in such conditions as renal colic, interstitial cystitis and inflammatory bowel disease by agents that interfere with mechanosensory transduction in the organs considered, including P2X3 and P2X2/3 receptor antagonists that are orally bioavailable and stable in vivo and agents that inhibit or enhance ATP release and breakdown.

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [45689]
    • Pharmacology and Therapeutics - Research Publications [387]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors