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dc.contributor.authorHaines, KJ
dc.contributor.authorBerney, S
dc.contributor.authorWarrillow, S
dc.contributor.authorDenehy, L
dc.date.accessioned2020-12-18T03:32:13Z
dc.date.available2020-12-18T03:32:13Z
dc.date.issued2018-02-05
dc.identifierpii: 276
dc.identifier.citationHaines, K. J., Berney, S., Warrillow, S. & Denehy, L. (2018). Long-term recovery following critical illness in an Australian cohort. JOURNAL OF INTENSIVE CARE, 6 (1), https://doi.org/10.1186/s40560-018-0276-x.
dc.identifier.issn2052-0492
dc.identifier.urihttp://hdl.handle.net/11343/255810
dc.description.abstractBackground: Almost all data on 5-year outcomes for critical care survivors come from North America and Europe. The aim of this study was to investigate long-term mortality, physical function, psychological outcomes and health-related quality of life in a mixed intensive care unit cohort in Australia. Methods: This longitudinal study evaluated 4- to 5-year outcomes. Physical function (six-minute walk test) and health-related quality of life (Short Form 36 Version 2) were compared to 1-year outcomes and population norms. New psychological data (Center for Epidemiological Studies-Depression, Impact of Events Scale) was collected at follow-up. Results: Of the 150 participants, 66 (44%) patients were deceased by follow-up. Fifty-six survivors were included with a mean (SD) age of 64 (14.2). Survivors' mean (SD) six-minute walk distance increased between 1 and 4 to 5 years (465.8 m (148.9) vs. 507.5 m (118.2)) (mean difference = - 24.5 m, CI - 58.3, 9.2, p = 0.15). Depressive symptoms were low: median (IQR) score of 7.0 (1.0-15.0). The mean level of post-traumatic stress symptoms was low-median (IQR) score of 1.0 (0-11.0)-with only 9 (16%) above the threshold for potentially disordered symptoms. Short-Form 36 Physical and Mental Component Scores did not change between 1 and 4 to 5 years (46.4 (7.9) vs. 46.7 (8.1) and 48.8 (13) vs. 48.8 (11.1)) and were within a standard deviation of normal. Conclusions: Outcomes of critical illness are not uniform across nations. Mortality was increased in this cohort; however, survivors achieved a high level of recovery for physical function and health-related quality of life with low psychological morbidity at follow-up. Trial registration: The trial was registered with the Australian New Zealand Clinical Trials Registry ACTRN12605000776606.
dc.languageEnglish
dc.publisherBMC
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleLong-term recovery following critical illness in an Australian cohort
dc.typeJournal Article
dc.identifier.doi10.1186/s40560-018-0276-x
melbourne.affiliation.departmentMelbourne School of Health Sciences
melbourne.affiliation.departmentSurgery (Austin & Northern Health)
melbourne.affiliation.departmentCritical Care
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleJournal of Intensive Care
melbourne.source.volume6
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1306145
melbourne.contributor.authorDenehy, Linda
melbourne.contributor.authorWarrillow, Stephen
melbourne.contributor.authorHaines, Kimberley
melbourne.contributor.authorBerney, Susan
dc.identifier.eissn2052-0492
melbourne.accessrightsOpen Access


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