Show simple item record

dc.contributor.authorMahanty, S
dc.contributor.authorPrigent, A
dc.contributor.authorGarraud, O
dc.date.accessioned2020-12-18T03:35:16Z
dc.date.available2020-12-18T03:35:16Z
dc.date.issued2015-05-29
dc.identifierpii: 10.1186/s12865-015-0095-y
dc.identifier.citationMahanty, S., Prigent, A. & Garraud, O. (2015). Immunogenicity of infectious pathogens and vaccine antigens. BMC IMMUNOLOGY, 16 (1), https://doi.org/10.1186/s12865-015-0095-y.
dc.identifier.issn1471-2172
dc.identifier.urihttp://hdl.handle.net/11343/255833
dc.description.abstractThe concept of the immunogenicity of an antigen is frequently encountered in the context of vaccine development, an area of intense interest currently due to the emergence or re-emergence of infectious pathogens with the potential for worldwide spread. However, the theoretical notion of immunogenicity as discussed in older textbooks of immunology needs reconsideration due to advances in our understanding of immunologic responses. Immunogenicity is a property that can either be a desirable attribute, for example in the generation of an effective protective immunity against infectious pathogens or an undesirable trait, for example when it relates to novel therapeutic compounds and drugs, where an immune response needs to be prevented or inhibited. In this Forum Article, we aimed to revisit the issue of immunogenicity to discuss a series of simple questions relevant to the concept that are frequently rephrased but incompletely resolved in the immunologic literature.
dc.languageEnglish
dc.publisherBMC
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleImmunogenicity of infectious pathogens and vaccine antigens
dc.typeJournal Article
dc.identifier.doi10.1186/s12865-015-0095-y
melbourne.affiliation.departmentDoherty Institute
melbourne.source.titleBMC Immunology
melbourne.source.volume16
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1310066
melbourne.contributor.authorMahanty, Siddhartha
dc.identifier.eissn1471-2172
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record