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dc.contributor.authorTomlinson, JE
dc.contributor.authorReef, VB
dc.contributor.authorBoston, RC
dc.contributor.authorJohnson, AL
dc.date.accessioned2020-12-18T03:40:43Z
dc.date.available2020-12-18T03:40:43Z
dc.date.issued2015-09
dc.identifier.citationTomlinson, J. E., Reef, V. B., Boston, R. C. & Johnson, A. L. (2015). The Association of Fibrinous Pleural Effusion with Survival and Complications in Horses with Pleuropneumonia (2002-2012): 74 Cases.. J Vet Intern Med, 29 (5), pp.1410-1417. https://doi.org/10.1111/jvim.13591.
dc.identifier.issn0891-6640
dc.identifier.urihttp://hdl.handle.net/11343/255873
dc.description.abstractBACKGROUND: Fibrinous parapneumonic pleural effusions are associated with decreased efficacy of pleural fluid drainage and increased risk of medical treatment failure in people, but similar associations have not been established in horses. HYPOTHESIS/OBJECTIVES: We hypothesized that fibrin deposition in the pleural cavity of horses with parapneumonic effusions increases the risk of poor outcome. ANIMALS: Seventy four horses with bacterial pleuropneumonia diagnosed by culture and cytology of tracheal aspirates, pleural fluid, or both, and pleural effusion diagnosed by ultrasonographic examination. METHODS: Retrospective study of cases was from 2002 to 2012. Information obtained from the medical records included signalment, history, sonographic findings, treatments, and outcome. The primary outcome investigated was survival and secondary outcomes were development of complications and surgical intervention. Fisher's exact test and logistic regression were applied for categorical variables. A t-test was used to find differences in continuous variables between groups. RESULTS: Seventy four horses met study criteria and 50 (68%) survived. Fibrinous pleural effusion was associated with higher respiratory rate and pleural fluid height at admission, necrotizing pneumonia, increased number of indwelling thoracic drains required for treatment, and decreased survival. CONCLUSIONS AND CLINICAL IMPORTANCE: Fibrin accumulation in parapneumonic effusions is associated with increased mortality. Direct fibrinolytic treatment might be indicated in affected horses.
dc.languageeng
dc.publisherWiley
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.titleThe Association of Fibrinous Pleural Effusion with Survival and Complications in Horses with Pleuropneumonia (2002-2012): 74 Cases.
dc.typeJournal Article
dc.identifier.doi10.1111/jvim.13591
melbourne.affiliation.departmentMedicine (St Vincent's)
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleJournal of Veterinary Internal Medicine
melbourne.source.volume29
melbourne.source.issue5
melbourne.source.pages1410-1417
dc.rights.licenseCC BY-NC
melbourne.elementsid1302090
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858045
melbourne.contributor.authorBoston, Raymond
dc.identifier.eissn1939-1676
melbourne.accessrightsOpen Access


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