Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

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    Author
    Engel, M; Sidwell, T; Vasanthakumar, A; Grigoriadis, G; Banerjee, A
    Date
    2013-01-01
    Source Title
    Clinical and Developmental Immunology
    Publisher
    HINDAWI LTD
    University of Melbourne Author/s
    Vasanthakumar, Ajithkumar
    Affiliation
    Microbiology and Immunology
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    Document Type
    Journal Article
    Citations
    Engel, M., Sidwell, T., Vasanthakumar, A., Grigoriadis, G. & Banerjee, A. (2013). Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors. CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2013, https://doi.org/10.1155/2013/617595.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/256053
    DOI
    10.1155/2013/617595
    Abstract
    Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

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