Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors
AuthorEngel, M; Sidwell, T; Vasanthakumar, A; Grigoriadis, G; Banerjee, A
Source TitleClinical and Developmental Immunology
University of Melbourne Author/sVasanthakumar, Ajithkumar
AffiliationMicrobiology and Immunology
Document TypeJournal Article
CitationsEngel, M., Sidwell, T., Vasanthakumar, A., Grigoriadis, G. & Banerjee, A. (2013). Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors. CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2013, https://doi.org/10.1155/2013/617595.
Access StatusOpen Access
Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.
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