Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

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Author
Engel, M; Sidwell, T; Vasanthakumar, A; Grigoriadis, G; Banerjee, ADate
2013-01-01Source Title
Clinical and Developmental ImmunologyPublisher
HINDAWI LTDUniversity of Melbourne Author/s
Vasanthakumar, AjithkumarAffiliation
Microbiology and ImmunologyMetadata
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Journal ArticleCitations
Engel, M., Sidwell, T., Vasanthakumar, A., Grigoriadis, G. & Banerjee, A. (2013). Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors. CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2013, https://doi.org/10.1155/2013/617595.Access Status
Open AccessAbstract
Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.
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