University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Anatomy and Neuroscience
  • Anatomy and Neuroscience - Research Publications
  • View Item
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Anatomy and Neuroscience
  • Anatomy and Neuroscience - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    Lung function imaging methods in Cystic Fibrosis pulmonary disease

    Thumbnail
    Download
    Published version (1.838Mb)

    Citations
    Scopus
    Web of Science
    Altmetric
    9
    6
    Author
    Kolodziej, M; de Veer, MJ; Cholewa, M; Egan, GF; Thompson, BR
    Date
    2017-05-17
    Source Title
    Respiratory Research
    Publisher
    BMC
    University of Melbourne Author/s
    Egan, Gary
    Affiliation
    Anatomy and Neuroscience
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Kolodziej, M., de Veer, M. J., Cholewa, M., Egan, G. F. & Thompson, B. R. (2017). Lung function imaging methods in Cystic Fibrosis pulmonary disease. RESPIRATORY RESEARCH, 18 (1), https://doi.org/10.1186/s12931-017-0578-x.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/256071
    DOI
    10.1186/s12931-017-0578-x
    Abstract
    Monitoring of pulmonary physiology is fundamental to the clinical management of patients with Cystic Fibrosis. The current standard clinical practise uses spirometry to assess lung function which delivers a clinically relevant functional readout of total lung function, however does not supply any visible or localised information. High Resolution Computed Tomography (HRCT) is a well-established current 'gold standard' method for monitoring lung anatomical changes in Cystic Fibrosis patients. HRCT provides excellent morphological information, however, the X-ray radiation dose can become significant if multiple scans are required to monitor chronic diseases such as cystic fibrosis. X-ray phase-contrast imaging is another emerging X-ray based methodology for Cystic Fibrosis lung assessment which provides dynamic morphological and functional information, albeit with even higher X-ray doses than HRCT. Magnetic Resonance Imaging (MRI) is a non-ionising radiation imaging method that is garnering growing interest among researchers and clinicians working with Cystic Fibrosis patients. Recent advances in MRI have opened up the possibilities to observe lung function in real time to potentially allow sensitive and accurate assessment of disease progression. The use of hyperpolarized gas or non-contrast enhanced MRI can be tailored to clinical needs. While MRI offers significant promise it still suffers from poor spatial resolution and the development of an objective scoring system especially for ventilation assessment.

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [53102]
    • Anatomy and Neuroscience - Research Publications [805]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors