Graphene foam as a biocompatible scaffold for culturing human neurons
AuthorD'Abaco, GM; Mattei, C; Nasr, BK; Hudson, EJ; Alshawaf, AJ; Chana, G; Everall, IP; Nayagam, B; Dottori, M; Skafidas, E
Source TitleRoyal Society Open Science
University of Melbourne Author/sSkafidas, Efstratios; Nasr, Babak; Chana, Gursharan; Everall, Ian; Nayagam, Bryony; Dottori, Mirella; D'Abaco, Giovanna Marisa; Mattei, Cristiana; HUDSON, EMMA; Alshawaf, Abdullah
AffiliationElectrical and Electronic Engineering
Audiology and Speech Pathology
Medicine and Radiology
Anatomy and Neuroscience
Florey Department of Neuroscience and Mental Health
Document TypeJournal Article
CitationsD'Abaco, G. M., Mattei, C., Nasr, B. K., Hudson, E. J., Alshawaf, A. J., Chana, G., Everall, I. P., Nayagam, B., Dottori, M. & Skafidas, E. (2018). Graphene foam as a biocompatible scaffold for culturing human neurons. ROYAL SOCIETY OPEN SCIENCE, 5 (3), https://doi.org/10.1098/rsos.171364.
Access StatusOpen Access
ARC Grant codeARC/FT130100514
In this study, we explore the use of electrically active graphene foam as a scaffold for the culture of human-derived neurons. Human embryonic stem cell (hESC)-derived cortical neurons fated as either glutamatergic or GABAergic neuronal phenotypes were cultured on graphene foam. We show that graphene foam is biocompatible for the culture of human neurons, capable of supporting cell viability and differentiation of hESC-derived cortical neurons. Based on the findings, we propose that graphene foam represents a suitable scaffold for engineering neuronal tissue and warrants further investigation as a model for understanding neuronal maturation, function and circuit formation.
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