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    Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank.

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    Author
    Alfaro-Almagro, F; Jenkinson, M; Bangerter, NK; Andersson, JLR; Griffanti, L; Douaud, G; Sotiropoulos, SN; Jbabdi, S; Hernandez-Fernandez, M; Vallee, E; ...
    Date
    2018-02-01
    Source Title
    NeuroImage
    Publisher
    Elsevier BV
    University of Melbourne Author/s
    Jenkinson, Mark
    Affiliation
    Centre for Neuroscience
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Alfaro-Almagro, F., Jenkinson, M., Bangerter, N. K., Andersson, J. L. R., Griffanti, L., Douaud, G., Sotiropoulos, S. N., Jbabdi, S., Hernandez-Fernandez, M., Vallee, E., Vidaurre, D., Webster, M., McCarthy, P., Rorden, C., Daducci, A., Alexander, D. C., Zhang, H., Dragonu, I., Matthews, P. M. ,... Smith, S. M. (2018). Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank.. Neuroimage, 166, pp.400-424. https://doi.org/10.1016/j.neuroimage.2017.10.034.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/256303
    DOI
    10.1016/j.neuroimage.2017.10.034
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770339
    Abstract
    UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline.

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