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    Staphylococcus aureus Prostatic abscess: a clinical case report and a review of the literature

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    Author
    Carroll, DE; Marr, I; Huang, GKL; Holt, DC; Tong, SYC; Boutlis, CS
    Date
    2017-07-21
    Source Title
    BMC Infectious Diseases
    Publisher
    BMC
    University of Melbourne Author/s
    Tong, Steven
    Affiliation
    Doherty Institute
    Metadata
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    Document Type
    Journal Article
    Citations
    Carroll, D. E., Marr, I., Huang, G. K. L., Holt, D. C., Tong, S. Y. C. & Boutlis, C. S. (2017). Staphylococcus aureus Prostatic abscess: a clinical case report and a review of the literature. BMC INFECTIOUS DISEASES, 17 (1), https://doi.org/10.1186/s12879-017-2605-4.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/256493
    DOI
    10.1186/s12879-017-2605-4
    Abstract
    BACKGROUND: Prostatic abscess is a rare complication of acute bacterial prostatitis and is most commonly caused by Enterobacteriaceae. We report on a case of prostatic abscess caused by Staphylococcus aureus and conduct a review of the literature. CASE PRESENTATIVE: We present a case of S. aureus prostatic abscess that was successfully treated with a combination of antibiotic and surgical therapy. The isolate was non–multidrug-resistant, methicillin-resistant Staphylococcus aureus and was genotyped as clonal complex 5, an emerging regional clone that is trimethoprim resistant and Panton-Valentine leukocidin positive. This current case report is the first to describe the use of clindamycin step-down therapy. A literature review identified a further 39 cases of S. aureus prostatic abscesses, of which 26 were methicillin resistant. CONCLUSION: S. aureus is an uncommon cause of prostatic abscess. Optimal management includes both antibiotic therapy and surgical drainage. Our use of clindamycin as step-down therapy was guided by its excellent prostatic penetration.

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