Discussing and prescribing expensive unfunded anticancer drugs in Australia
Web of Science
AuthorKarikios, DJ; Mileshkin, L; Martin, A; Ferraro, D; Stockler, MR
Source TitleESMO Open
PublisherBMJ PUBLISHING GROUP
Document TypeJournal Article
CitationsKarikios, D. J., Mileshkin, L., Martin, A., Ferraro, D. & Stockler, M. R. (2017). Discussing and prescribing expensive unfunded anticancer drugs in Australia. ESMO OPEN, 2 (2), https://doi.org/10.1136/esmoopen-2017-000170.
Access StatusOpen Access
OBJECTIVE: Australia has a publicly funded universal healthcare system which heavily subsidises the cost of most registered anticancer drugs. The use of anticancer drugs that are unfunded, that is, not subsidised by the government, entails substantial out-of-pocket costs for patients. We sought to determine how frequently Australian medical oncologists discuss and prescribe unfunded anticancer drugs, and their attitudes and beliefs about their use. METHODS: Members of the Medical Oncology Group of Australia (MOGA) completed an online survey about their clinical practices over a recent 3-month period. A negative binomial regression model was used to examine the influence of respondent characteristics on the rate of discussions about, and prescription of, unfunded anticancer drugs. RESULTS: Of the 154 respondents (27% of 575 MOGA members), 92% had discussed and 68% had prescribed at least one unfunded anticancer drug in the last 3 months. Respondents reported discussing unfunded anticancer drugs with an average of 2.5 patients per month (95% CI 2.1 to 2.9), and prescribed them to an average of 0.9 patients per month (95% CI 0.7 to 1.2). The rate of discussing unfunded anticancer drugs was associated with being fully qualified (p=0.01), and being in a metropolitan practice (p=0.009), the rate of prescription was associated only with being in metropolitan practice (p=0.006). The concerns about discussing and prescribing unfunded anticancer drugs rated most important were as follows: 'potential to cause financial hardship' and 'difficulty for patients to evaluate the benefits versus the costs'. CONCLUSIONS: Australian medical oncologists frequently discuss and prescribe unfunded anticancer drugs, and are concerned about their patients having to face difficult decisions and financial hardship. Further research is needed to better understand the factors that affect how oncologists and patients value expensive, unfunded anticancer drugs.
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