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dc.contributor.authorWhiteford, N
dc.contributor.authorSkelly, T
dc.contributor.authorCurtis, C
dc.contributor.authorRitchie, ME
dc.contributor.authorLoehr, A
dc.contributor.authorZaranek, AW
dc.contributor.authorAbnizova, I
dc.contributor.authorBrown, C
dc.date.accessioned2020-12-21T02:01:10Z
dc.date.available2020-12-21T02:01:10Z
dc.date.issued2009-09-01
dc.identifierpii: btp383
dc.identifier.citationWhiteford, N., Skelly, T., Curtis, C., Ritchie, M. E., Loehr, A., Zaranek, A. W., Abnizova, I. & Brown, C. (2009). Swift: primary data analysis for the Illumina Solexa sequencing platform. BIOINFORMATICS, 25 (17), pp.2194-2199. https://doi.org/10.1093/bioinformatics/btp383.
dc.identifier.issn1367-4803
dc.identifier.urihttp://hdl.handle.net/11343/256749
dc.description.abstractMOTIVATION: Primary data analysis methods are of critical importance in second generation DNA sequencing. Improved methods have the potential to increase yield and reduce the error rates. Openly documented analysis tools enable the user to understand the primary data, this is important for the optimization and validity of their scientific work. RESULTS: In this article, we describe Swift, a new tool for performing primary data analysis on the Illumina Solexa Sequencing Platform. Swift is the first tool, outside of the vendors own software, which completes the full analysis process, from raw images through to base calls. As such it provides an alternative to, and independent validation of, the vendor supplied tool. Our results show that Swift is able to increase yield by 13.8%, at comparable error rate.
dc.languageEnglish
dc.publisherOXFORD UNIV PRESS
dc.titleSwift: primary data analysis for the Illumina Solexa sequencing platform
dc.typeJournal Article
dc.identifier.doi10.1093/bioinformatics/btp383
melbourne.affiliation.departmentMedical Biology (W.E.H.I.)
melbourne.source.titleBioinformatics
melbourne.source.volume25
melbourne.source.issue17
melbourne.source.pages2194-2199
dc.rights.licenseCC BY-NC
melbourne.elementsid1230396
melbourne.contributor.authorRitchie, Matthew
dc.identifier.eissn1460-2059
melbourne.accessrightsOpen Access


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