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dc.contributor.authorParacchini, S
dc.contributor.authorAng, QW
dc.contributor.authorStanley, FJ
dc.contributor.authorMonaco, AP
dc.contributor.authorPennell, CE
dc.contributor.authorWhitehouse, AJO
dc.date.accessioned2020-12-21T02:04:42Z
dc.date.available2020-12-21T02:04:42Z
dc.date.issued2011-03-01
dc.identifier.citationParacchini, S., Ang, Q. W., Stanley, F. J., Monaco, A. P., Pennell, C. E. & Whitehouse, A. J. O. (2011). Analysis of dyslexia candidate genes in the Raine cohort representing the general Australian population. GENES BRAIN AND BEHAVIOR, 10 (2), pp.158-165. https://doi.org/10.1111/j.1601-183X.2010.00651.x.
dc.identifier.issn1601-1848
dc.identifier.urihttp://hdl.handle.net/11343/256775
dc.description.abstractSeveral genes have been suggested as dyslexia candidates. Some of these candidate genes have been recently shown to be associated with literacy measures in sample cohorts derived from the general population. Here, we have conducted an association study in a novel sample derived from the Australian population (the Raine cohort) to further investigate the role of dyslexia candidate genes. We analysed markers, previously reported to be associated with dyslexia, located within the MRPL19/C2ORF3, KIAA0319, DCDC2 and DYX1C1 genes in a sample of 520 individuals and tested them for association with reading and spelling measures. Association signals were detected for several single nucleotide polymorphisms (SNPs) within DYX1C1 with both the reading and spelling tests. The high linkage disequilibrium (LD) we observed across the DYX1C1 gene suggests that the association signal might not be refined by further genetic mapping.
dc.languageEnglish
dc.publisherWILEY
dc.titleAnalysis of dyslexia candidate genes in the Raine cohort representing the general Australian population
dc.typeJournal Article
dc.identifier.doi10.1111/j.1601-183X.2010.00651.x
melbourne.affiliation.departmentMelbourne School of Population and Global Health
melbourne.source.titleGenes, Brain and Behavior
melbourne.source.volume10
melbourne.source.issue2
melbourne.source.pages158-165
dc.rights.licenseCC BY
melbourne.elementsid1231227
melbourne.contributor.authorStanley, Fiona
dc.identifier.eissn1601-183X
melbourne.accessrightsOpen Access


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