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    Target product profiles for the diagnosis of Taenia solium taeniasis, neurocysticercosis and porcine cysticercosis

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    Author
    Donadeu, M; Fahrion, AS; Olliaro, PL; Abela-Ridder, B
    Date
    2017-09-01
    Source Title
    PLoS Neglected Tropical Diseases
    Publisher
    PUBLIC LIBRARY SCIENCE
    University of Melbourne Author/s
    Donadeu, Meritxell
    Affiliation
    Veterinary and Agricultural Sciences
    Metadata
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    Document Type
    Journal Article
    Citations
    Donadeu, M., Fahrion, A. S., Olliaro, P. L. & Abela-Ridder, B. (2017). Target product profiles for the diagnosis of Taenia solium taeniasis, neurocysticercosis and porcine cysticercosis. PLOS NEGLECTED TROPICAL DISEASES, 11 (9), https://doi.org/10.1371/journal.pntd.0005875.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/256941
    DOI
    10.1371/journal.pntd.0005875
    Abstract
    Target Product Profiles (TPPs) are process tools providing product requirements to guide researchers, developers and manufacturers in their efforts to develop effective and useful products such as biologicals, drugs or diagnostics. During a WHO Stakeholders Meeting on Taenia solium diagnostics, several TPPs were initiated to address diagnostic needs for different stages in the parasite's transmission (taeniasis, human and porcine cysticercosis). Following the meeting, draft TPPs were completed and distributed for consultation to 100 people/organizations, including experts in parasitology, human and pig cysticercosis, diagnostic researchers and manufacturers, international organizations working with neglected or zoonotic diseases, Ministries of Health and Ministries of Livestock in some of the endemic countries, WHO regional offices and other interested parties. There were 53 respondents. All comments and feedback received were considered and discussions were held with different experts according to their area of expertise. The comments were consolidated and final TPPs are presented here. They are considered to be live documents which are likely to undergo review and updating in the future when new knowledge and technologies become available.

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