Cervical Cancer Prevention Through HPV Vaccination in Low- and Middle-Income Countries in Asia

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Toh, ZQ; Licciardi, PV; Russell, FM; Garland, SM; Batmunkh, T; Mulholland, EKDate
2017-09-27Source Title
Asian Pacific Journal of Cancer PreventionAffiliation
Paediatrics (RCH)Obstetrics and Gynaecology
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Toh, Z. Q., Licciardi, P. V., Russell, F. M., Garland, S. M., Batmunkh, T. & Mulholland, E. K. (2017). Cervical Cancer Prevention Through HPV Vaccination in Low- and Middle-Income Countries in Asia. Asian Pac J Cancer Prev, 18 (9), pp.2339-2343. https://doi.org/10.22034/APJCP.2017.18.9.2339.Access Status
Open AccessOpen Access at PMC
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720633Abstract
Cervical cancer is ranked the first or second most common cancer in women of low- and middle-income countries
(LMICs) in Asia. Cervical cancer is almost exclusively caused by human papillomavirus (HPV), and majority of the
cases can be prevented with the use of HPV vaccines. The HPV vaccines have demonstrated high vaccine efficacies
against HPV infection and cervical cancer precursors in clinical and post-marketing studies, and are in use in most
high-income countries. However, their use in LMICs are limited mainly due to the high costs and logistics in delivering
multiple doses of the vaccine. Other issues such as the safety of the vaccines, social and cultural factors, as well as
poor knowledge and awareness of the virus have also contributed to the low uptake of the vaccine. This mini-review
focuses on the need for HPV vaccine implementation in Asia given the substantial disease burden and underuse of HPV
vaccines in LMICs in this region. In addition, the progress towards HPV vaccine introduction, and barriers preventing
further rollout of these essential, life-saving vaccines are also discussed in this article.
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