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dc.contributor.authorMaksimovic, J
dc.contributor.authorGordon, L
dc.contributor.authorOshlack, A
dc.date.accessioned2020-12-21T02:38:25Z
dc.date.available2020-12-21T02:38:25Z
dc.date.issued2012-01-01
dc.identifierpii: gb-2012-13-6-r44
dc.identifier.citationMaksimovic, J., Gordon, L. & Oshlack, A. (2012). SWAN: Subset-quantile Within Array Normalization for Illumina Infinium HumanMethylation450 BeadChips. GENOME BIOLOGY, 13 (6), https://doi.org/10.1186/gb-2012-13-6-r44.
dc.identifier.issn1474-760X
dc.identifier.urihttp://hdl.handle.net/11343/257008
dc.description.abstractDNA methylation is the most widely studied epigenetic mark and is known to be essential to normal development and frequently disrupted in disease. The Illumina HumanMethylation450 BeadChip assays the methylation status of CpGs at 485,577 sites across the genome. Here we present Subset-quantile Within Array Normalization (SWAN), a new method that substantially improves the results from this platform by reducing technical variation within and between arrays. SWAN is available in the minfi Bioconductor package.
dc.languageEnglish
dc.publisherBMC
dc.titleSWAN: Subset-quantile Within Array Normalization for Illumina Infinium HumanMethylation450 BeadChips
dc.typeJournal Article
dc.identifier.doi10.1186/gb-2012-13-6-r44
melbourne.affiliation.departmentSchool of Physics
melbourne.affiliation.departmentPaediatrics (RCH)
melbourne.affiliation.departmentClinical Pathology
melbourne.source.titleGenome Biology
melbourne.source.volume13
melbourne.source.issue6
dc.rights.licenseCC BY
melbourne.elementsid1234914
melbourne.contributor.authorOshlack, Alicia
melbourne.contributor.authorMaksimovic, Jovana
melbourne.contributor.authorGordon, Lavinia
dc.identifier.eissn1474-760X
melbourne.accessrightsOpen Access


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