The evolving world of pseudoenzymes: proteins, prejudice and zombies

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Author
Eyers, PA; Murphy, JMDate
2016-11-11Source Title
BMC BiologyPublisher
BIOMED CENTRAL LTDUniversity of Melbourne Author/s
Murphy, JamesAffiliation
Medical Biology (W.E.H.I.)Metadata
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Journal ArticleCitations
Eyers, P. A. & Murphy, J. M. (2016). The evolving world of pseudoenzymes: proteins, prejudice and zombies. BMC BIOLOGY, 14 (1), https://doi.org/10.1186/s12915-016-0322-x.Access Status
Open AccessAbstract
Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.
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