The evolving world of pseudoenzymes: proteins, prejudice and zombies
AuthorEyers, PA; Murphy, JM
Source TitleBMC Biology
PublisherBIOMED CENTRAL LTD
University of Melbourne Author/sMurphy, James
AffiliationMedical Biology (W.E.H.I.)
Document TypeJournal Article
CitationsEyers, P. A. & Murphy, J. M. (2016). The evolving world of pseudoenzymes: proteins, prejudice and zombies. BMC BIOLOGY, 14 (1), https://doi.org/10.1186/s12915-016-0322-x.
Access StatusOpen Access
Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.
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