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dc.contributor.authorSeneviratne, U
dc.contributor.authorCook, MJ
dc.contributor.authorD'Souza, WJ
dc.date.accessioned2020-12-21T03:24:56Z
dc.date.available2020-12-21T03:24:56Z
dc.date.issued2017-09-25
dc.identifier.citationSeneviratne, U., Cook, M. J. & D'Souza, W. J. (2017). Electroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes. FRONTIERS IN NEUROLOGY, 8 (SEP), https://doi.org/10.3389/fneur2017.00499.
dc.identifier.issn1664-2295
dc.identifier.urihttp://hdl.handle.net/11343/257194
dc.description.abstractGenetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized spike-wave complex. Other classic EEG abnormalities are polyspikes, epileptiform K-complexes and sleep spindles, polyspike-wave discharges, occipital intermittent rhythmic delta activity, eye-closure sensitivity, fixation-off sensitivity, and photoparoxysmal response. However, admixed with typical changes, atypical epileptiform discharges are also commonly seen in GGE. There are circadian variations of generalized epileptiform discharges. Sleep, sleep deprivation, hyperventilation, intermittent photic stimulation, eye closure, and fixation-off are often used as activation techniques to increase the diagnostic yield of EEG recordings. Reflex seizure-related EEG abnormalities can be elicited by the use of triggers such as cognitive tasks and pattern stimulation during the EEG recording in selected patients. Distinct electrographic abnormalities to help classification can be identified among different electroclinical syndromes.
dc.languageEnglish
dc.publisherFRONTIERS MEDIA SA
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleElectroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes
dc.typeJournal Article
dc.identifier.doi10.3389/fneur2017.00499
melbourne.affiliation.departmentEngineering and Information Technology
melbourne.affiliation.departmentMedicine (St Vincent's)
melbourne.affiliation.facultyEngineering and Information Technology
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleFrontiers in Neurology
melbourne.source.volume8
melbourne.source.issueSEP
dc.rights.licenseCC BY
melbourne.elementsid1253901
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622315
melbourne.contributor.authorD'Souza, Wendyl
melbourne.contributor.authorCook, Mark
melbourne.contributor.authorSeneviratne, Udaya
dc.identifier.eissn1664-2295
melbourne.accessrightsOpen Access


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