Show simple item record

dc.contributor.authorDe Tommasi, AS
dc.contributor.authorOtranto, D
dc.contributor.authorFurlanello, T
dc.contributor.authorTasca, S
dc.contributor.authorCantacessi, C
dc.contributor.authorBreitschwerdt, EB
dc.contributor.authorStanneck, D
dc.contributor.authorDantas-Torres, F
dc.contributor.authorBaneth, G
dc.contributor.authorCapelli, G
dc.contributor.authorde Caprariis, D
dc.date.accessioned2020-12-21T03:27:59Z
dc.date.available2020-12-21T03:27:59Z
dc.date.issued2014-12-02
dc.identifierpii: s13071-014-0534-2
dc.identifier.citationDe Tommasi, A. S., Otranto, D., Furlanello, T., Tasca, S., Cantacessi, C., Breitschwerdt, E. B., Stanneck, D., Dantas-Torres, F., Baneth, G., Capelli, G. & de Caprariis, D. (2014). Evaluation of blood and bone marrow in selected canine vector-borne diseases. PARASITES & VECTORS, 7 (1), https://doi.org/10.1186/s13071-014-0534-2.
dc.identifier.issn1756-3305
dc.identifier.urihttp://hdl.handle.net/11343/257216
dc.description.abstractBACKGROUND: Bone marrow (BM) is a major hematopoietic organ that can harbour a variety of vector-borne pathogens; however, knowledge of BM pathological changes in dogs infected with vector-borne pathogens is limited. Thus, the aim of the present study was to assess the pathological changes in canine BM associated with natural infections by four vector-borne pathogens, as well as to determine the relationships between such changes and abnormalities of the peripheral blood. METHODS: Cytological disorders and pathological changes of the BM of 83 dogs naturally-infected with one or more of four vector-borne pathogens (i.e., Anaplasma platys, Leishmania infantum, Babesia vogeli and Hepatozoon canis) were evaluated and compared with the corresponding hematological findings. RESULTS: Dysgranulopoiesis and dysmegakaryocytopoiesis were the most frequently observed BM abnormalities in infected dogs. Erythroid suppression, and lymphocytic, monocytic and macrophage hyperplasia were also observed. Interestingly, associations between suppression and hyperplasia of specific cell lines in the marrow and corresponding changes in numbers of circulating peripheral blood cells were not observed. CONCLUSIONS: Infections with one or more of the vector-borne pathogens examined in this study should be considered as differential diagnoses for secondary dysmyelopoiesis.
dc.languageEnglish
dc.publisherBIOMED CENTRAL LTD
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleEvaluation of blood and bone marrow in selected canine vector-borne diseases
dc.typeJournal Article
dc.identifier.doi10.1186/s13071-014-0534-2
melbourne.affiliation.departmentVeterinary Biosciences
melbourne.source.titleParasites and Vectors
melbourne.source.volume7
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1254346
melbourne.contributor.authorCantacessi, Cinzia
dc.identifier.eissn1756-3305
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record