Show simple item record

dc.contributor.authorLiu, T
dc.contributor.authorLin, Y
dc.contributor.authorWen, X
dc.contributor.authorJorissen, RN
dc.contributor.authorGilson, MK
dc.date.accessioned2020-12-21T03:39:57Z
dc.date.available2020-12-21T03:39:57Z
dc.date.issued2007-01-01
dc.identifierpii: gkl999
dc.identifier.citationLiu, T., Lin, Y., Wen, X., Jorissen, R. N. & Gilson, M. K. (2007). BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities. NUCLEIC ACIDS RESEARCH, 35 (Database issue), pp.D198-D201. https://doi.org/10.1093/nar/gkl999.
dc.identifier.issn0305-1048
dc.identifier.urihttp://hdl.handle.net/11343/257301
dc.description.abstractBindingDB (http://www.bindingdb.org) is a publicly accessible database currently containing approximately 20,000 experimentally determined binding affinities of protein-ligand complexes, for 110 protein targets including isoforms and mutational variants, and approximately 11,000 small molecule ligands. The data are extracted from the scientific literature, data collection focusing on proteins that are drug-targets or candidate drug-targets and for which structural data are present in the Protein Data Bank. The BindingDB website supports a range of query types, including searches by chemical structure, substructure and similarity; protein sequence; ligand and protein names; affinity ranges and molecular weight. Data sets generated by BindingDB queries can be downloaded in the form of annotated SDfiles for further analysis, or used as the basis for virtual screening of a compound database uploaded by the user. The data in BindingDB are linked both to structural data in the PDB via PDB IDs and chemical and sequence searches, and to the literature in PubMed via PubMed IDs.
dc.languageEnglish
dc.publisherOXFORD UNIV PRESS
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.titleBindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities
dc.typeJournal Article
dc.identifier.doi10.1093/nar/gkl999
melbourne.affiliation.departmentMedical Biology (W.E.H.I.)
melbourne.source.titleNucleic Acids Research
melbourne.source.volume35
melbourne.source.issueDatabase issue
melbourne.source.pagesD198-D201
dc.rights.licenseCC BY-NC
melbourne.elementsid1263014
melbourne.contributor.authorJorissen, Robert
dc.identifier.eissn1362-4962
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record