dc.contributor.author | de Jonge, MD | |
dc.contributor.author | Ryan, CG | |
dc.contributor.author | Jacobsen, CJ | |
dc.date.accessioned | 2020-12-21T03:57:26Z | |
dc.date.available | 2020-12-21T03:57:26Z | |
dc.date.issued | 2014-09-01 | |
dc.identifier | pii: S160057751401621X | |
dc.identifier.citation | de Jonge, M. D., Ryan, C. G. & Jacobsen, C. J. (2014). X-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens. JOURNAL OF SYNCHROTRON RADIATION, 21 (Pt 5), pp.1031-1047. https://doi.org/10.1107/S160057751401621X. | |
dc.identifier.issn | 0909-0495 | |
dc.identifier.uri | http://hdl.handle.net/11343/257426 | |
dc.description.abstract | X-ray nanoprobes require coherent illumination to achieve optic-limited resolution, and so will benefit directly from diffraction-limited storage rings. Here, the example of high-resolution X-ray fluorescence tomography is focused on as one of the most voracious demanders of coherent photons, since the detected signal is only a small fraction of the incident flux. Alternative schemes are considered for beam delivery, sample scanning and detectors. One must consider as well the steps before and after the X-ray experiment: sample preparation and examination conditions, and analysis complexity due to minimum dose requirements and self-absorption. By understanding the requirements and opportunities for nanoscale fluorescence tomography, one gains insight into the R&D challenges in optics and instrumentation needed to fully exploit the source advances that diffraction-limited storage rings offer. | |
dc.language | English | |
dc.publisher | INT UNION CRYSTALLOGRAPHY | |
dc.title | X-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens | |
dc.type | Journal Article | |
dc.identifier.doi | 10.1107/S160057751401621X | |
melbourne.affiliation.department | School of Physics | |
melbourne.source.title | Journal of Synchrotron Radiation | |
melbourne.source.volume | 21 | |
melbourne.source.issue | Pt 5 | |
melbourne.source.pages | 1031-1047 | |
dc.rights.license | CC BY | |
melbourne.elementsid | 1272734 | |
melbourne.contributor.author | Ryan, Christopher | |
dc.identifier.eissn | 1600-5775 | |
melbourne.accessrights | Open Access | |