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dc.contributor.authorde Jonge, MD
dc.contributor.authorRyan, CG
dc.contributor.authorJacobsen, CJ
dc.date.accessioned2020-12-21T03:57:26Z
dc.date.available2020-12-21T03:57:26Z
dc.date.issued2014-09-01
dc.identifierpii: S160057751401621X
dc.identifier.citationde Jonge, M. D., Ryan, C. G. & Jacobsen, C. J. (2014). X-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens. JOURNAL OF SYNCHROTRON RADIATION, 21 (Pt 5), pp.1031-1047. https://doi.org/10.1107/S160057751401621X.
dc.identifier.issn0909-0495
dc.identifier.urihttp://hdl.handle.net/11343/257426
dc.description.abstractX-ray nanoprobes require coherent illumination to achieve optic-limited resolution, and so will benefit directly from diffraction-limited storage rings. Here, the example of high-resolution X-ray fluorescence tomography is focused on as one of the most voracious demanders of coherent photons, since the detected signal is only a small fraction of the incident flux. Alternative schemes are considered for beam delivery, sample scanning and detectors. One must consider as well the steps before and after the X-ray experiment: sample preparation and examination conditions, and analysis complexity due to minimum dose requirements and self-absorption. By understanding the requirements and opportunities for nanoscale fluorescence tomography, one gains insight into the R&D challenges in optics and instrumentation needed to fully exploit the source advances that diffraction-limited storage rings offer.
dc.languageEnglish
dc.publisherINT UNION CRYSTALLOGRAPHY
dc.titleX-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens
dc.typeJournal Article
dc.identifier.doi10.1107/S160057751401621X
melbourne.affiliation.departmentSchool of Physics
melbourne.source.titleJournal of Synchrotron Radiation
melbourne.source.volume21
melbourne.source.issuePt 5
melbourne.source.pages1031-1047
dc.rights.licenseCC BY
melbourne.elementsid1272734
melbourne.contributor.authorRyan, Christopher
dc.identifier.eissn1600-5775
melbourne.accessrightsOpen Access


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