Shaping Innate Lymphoid Cell Diversity

Download
Author
Huang, Q; Seillet, C; Belz, GTDate
2017-11-16Source Title
Frontiers in ImmunologyPublisher
FRONTIERS MEDIA SAAffiliation
Medical Biology (W.E.H.I.)Metadata
Show full item recordDocument Type
Journal ArticleCitations
Huang, Q., Seillet, C. & Belz, G. T. (2017). Shaping Innate Lymphoid Cell Diversity. FRONTIERS IN IMMUNOLOGY, 8 (NOV), https://doi.org/10.3389/fimmu.2017.01569.Access Status
Open AccessOpen Access at PMC
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697340Abstract
Innate lymphoid cells (ILCs) are a key cell type that are enriched at mucosal surfaces and within tissues. Our understanding of these cells is growing rapidly. Paradoxically, these cells play a role in maintaining tissue integrity but they also function as key drivers of allergy and inflammation. We present here the most recent understanding of how genomics has provided significant insight into how ILCs are generated and the enormous heterogeneity present within the canonical subsets. This has allowed the generation of a detailed blueprint for ILCs to become highly sensitive and adaptive sensors of environmental changes and therefore exquisitely equipped to protect immune surfaces.
Export Reference in RIS Format
Endnote
- Click on "Export Reference in RIS Format" and choose "open with... Endnote".
Refworks
- Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References