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    STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease.

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    Author
    Sachdev, PS; Lo, JW; Crawford, JD; Mellon, L; Hickey, A; Williams, D; Bordet, R; Mendyk, A-M; Gelé, P; Deplanque, D; ...
    Date
    2017
    Source Title
    Alzheimer's & dementia (Amsterdam, Netherlands)
    Publisher
    Wiley
    University of Melbourne Author/s
    Brodtmann, Amy; Cumming, Toby; Donnan, Geoffrey; Werden, Emile
    Affiliation
    Medicine and Radiology
    Physiotherapy
    Florey Department of Neuroscience and Mental Health
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Sachdev, P. S., Lo, J. W., Crawford, J. D., Mellon, L., Hickey, A., Williams, D., Bordet, R., Mendyk, A. -M., Gelé, P., Deplanque, D., Bae, H. -J., Lim, J. -S., Brodtmann, A., Werden, E., Cumming, T., Köhler, S., Verhey, F. R. J., Dong, Y. -H., Tan, H. H. ,... STROKOG (2017). STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease.. Alzheimers Dement (Amst), 7 (1), pp.11-23. https://doi.org/10.1016/j.dadm.2016.10.006.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/257536
    DOI
    10.1016/j.dadm.2016.10.006
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257024
    NHMRC Grant code
    NHMRC/1094974
    NHMRC/1045617
    Abstract
    INTRODUCTION: The Stroke and Cognition consortium (STROKOG) aims to facilitate a better understanding of the determinants of vascular contributions to cognitive disorders and help improve the diagnosis and treatment of vascular cognitive disorders (VCD). METHODS: Longitudinal studies with ≥75 participants who had suffered or were at risk of stroke or TIA and which evaluated cognitive function were invited to join STROKOG. The consortium will facilitate projects investigating rates and patterns of cognitive decline, risk factors for VCD, and biomarkers of vascular dementia. RESULTS: Currently, STROKOG includes 25 (21 published) studies, with 12,092 participants from five continents. The duration of follow-up ranges from 3 months to 21 years. DISCUSSION: Although data harmonization will be a key challenge, STROKOG is in a unique position to reuse and combine international cohort data and fully explore patient level characteristics and outcomes. STROKOG could potentially transform our understanding of VCD and have a worldwide impact on promoting better vascular cognitive outcomes.

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