MACROPHAGE TUMOR-CELL LINE AND PLASMINOGEN ACTIVATOR - POTENTIAL MODEL SYSTEM FOR MACROPHAGE REGULATION OF ENZYME-PRODUCTION

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HAMILTON, JA; RALPH, P; MOORE, MASDate
1978-01-01Source Title
Journal of Experimental MedicinePublisher
ROCKEFELLER UNIV PRESSUniversity of Melbourne Author/s
Hamilton, JohnAffiliation
Medicine and RadiologyMetadata
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Journal ArticleCitations
HAMILTON, J. A., RALPH, P. & MOORE, M. A. S. (1978). MACROPHAGE TUMOR-CELL LINE AND PLASMINOGEN ACTIVATOR - POTENTIAL MODEL SYSTEM FOR MACROPHAGE REGULATION OF ENZYME-PRODUCTION. JOURNAL OF EXPERIMENTAL MEDICINE, 148 (3), pp.811-816. https://doi.org/10.1084/jem.148.3.811.Access Status
Open AccessAbstract
The macrophage cell line, RAW264.10, synthesizes and secretes plasminogen activator. Production of this enzyme is inhibited by low concentrations of glucocorticoids and increased by phorbol myristate acetate. It is proposed that this line could be a suitable model for the regulation of enzyme synthesis by mouse peritoneal macrophages.
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