MACROPHAGE TUMOR-CELL LINE AND PLASMINOGEN ACTIVATOR - POTENTIAL MODEL SYSTEM FOR MACROPHAGE REGULATION OF ENZYME-PRODUCTION

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    Author
    HAMILTON, JA; RALPH, P; MOORE, MAS
    Date
    1978-01-01
    Source Title
    Journal of Experimental Medicine
    Publisher
    ROCKEFELLER UNIV PRESS
    University of Melbourne Author/s
    Hamilton, John
    Affiliation
    Medicine and Radiology
    Metadata
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    Document Type
    Journal Article
    Citations
    HAMILTON, J. A., RALPH, P. & MOORE, M. A. S. (1978). MACROPHAGE TUMOR-CELL LINE AND PLASMINOGEN ACTIVATOR - POTENTIAL MODEL SYSTEM FOR MACROPHAGE REGULATION OF ENZYME-PRODUCTION. JOURNAL OF EXPERIMENTAL MEDICINE, 148 (3), pp.811-816. https://doi.org/10.1084/jem.148.3.811.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/257692
    DOI
    10.1084/jem.148.3.811
    Abstract
    The macrophage cell line, RAW264.10, synthesizes and secretes plasminogen activator. Production of this enzyme is inhibited by low concentrations of glucocorticoids and increased by phorbol myristate acetate. It is proposed that this line could be a suitable model for the regulation of enzyme synthesis by mouse peritoneal macrophages.

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