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    Invasive Fungal Rhinosinusitis versus Bacterial Rhinosinusitis with Orbital Complications: A Case-Control Study

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    Author
    Piromchai, P; Thanaviratananich, S
    Date
    2013-01-01
    Source Title
    The Scientific World Journal
    Publisher
    HINDAWI PUBLISHING CORPORATION
    University of Melbourne Author/s
    Piromchai, Patorn
    Affiliation
    Otolaryngology
    Metadata
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    Document Type
    Journal Article
    Citations
    Piromchai, P. & Thanaviratananich, S. (2013). Invasive Fungal Rhinosinusitis versus Bacterial Rhinosinusitis with Orbital Complications: A Case-Control Study. SCIENTIFIC WORLD JOURNAL, 2013, https://doi.org/10.1155/2013/453297.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/257836
    DOI
    10.1155/2013/453297
    Abstract
    BACKGROUND: Invasive fungal rhinosinusitis with orbital complications (IFSwOC) is a life-threatening condition. The incidence of mortality has been reported to be up to 80 percent. This study was conducted to determine the risk factors, presentations, clinical, and imaging findings that could help to manage this condition promptly. METHODS: We conducted a case-control study of 100 patients suffering from rhinosinusitis with orbital complications. The risk factors, clinical presentations, radiological findings, medical and surgical managements, durations of hospital stay, and mortality rate data were collected. RESULTS: Sixty-five patients were diagnosed with IFSwOC, while the other thirty-five patients composed the control group. The most important risk factor for IFSwOC was diabetes mellitus. Visual loss and diplopia were the significant symptom predictors. The significant clinical predictors were nasal crust, oculomotor nerve, and optic nerve involvement. The CT findings of IFSwOC were sinus wall erosion and hyperdensity lesions. The mortality rate was 25.71 percent in the IFSwOC group and 3.17 percent in the control group. CONCLUSIONS: Invasive fungal rhinosinusitis with orbital complications is symptomatic of a high mortality rate. The awareness of a patient's risk factors, the presenting symptoms, signs of fungal invasion, and aggressive management will determine the success of any treatment procedures.

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