Show simple item record

dc.contributor.authorChua, J
dc.contributor.authorLim, B
dc.contributor.authorFenwick, EK
dc.contributor.authorGan, ATL
dc.contributor.authorTan, AG
dc.contributor.authorLamoureux, E
dc.contributor.authorMitchell, P
dc.contributor.authorWang, JJ
dc.contributor.authorWong, TY
dc.contributor.authorCheng, C-Y
dc.date.accessioned2020-12-22T04:04:48Z
dc.date.available2020-12-22T04:04:48Z
dc.date.issued2017-01-27
dc.identifierpii: PONE-D-16-46437
dc.identifier.citationChua, J., Lim, B., Fenwick, E. K., Gan, A. T. L., Tan, A. G., Lamoureux, E., Mitchell, P., Wang, J. J., Wong, T. Y. & Cheng, C. -Y. (2017). Prevalence, Risk Factors, and Impact of Undiagnosed Visually Significant Cataract: The Singapore Epidemiology of Eye Diseases Study. PLOS ONE, 12 (1), https://doi.org/10.1371/journal.pone.0170804.
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/11343/257989
dc.description.abstractOBJECTIVE: To determine the prevalence, risk factors, and impact of undiagnosed visually significant cataract in an Asian population. METHODS: The Singapore Epidemiology of Eye Diseases is a population-based study where 8,697 adults of Malay, Indian, and Chinese ethnicities aged > 40 years were invited for an eye examination, including lens photograph, to establish cataract diagnosis. Visually significant cataract was defined by Wisconsin Cataract Grading System and a best-corrected visual acuity <20/40 with cataract as the primary cause of vision impairment. Participants were deemed 'undiagnosed' if they had visually significant cataract and reported no prior physician diagnosis of cataract. Visual functioning (VF) was assessed with the VF-11 questionnaire validated using Rasch analysis. RESULTS: Among the 925 participants with visually significant cataract, 636 (68.8%) were unaware of their cataract status. Age-standardized prevalence varied according to ethnicity, with Malays having higher rates than Chinese and Indians. Factors independently associated with having undiagnosed visually significant cataract were: Malay ethnicity, lower educational attainment, in employment, and without a history of diabetes (all P<0.05). In those with undiagnosed visually significant cataract, half had bilateral visual impairment, which was significantly associated with 24.8% poorer visual functioning compared to those with unilateral visual impairment (P<0.001). CONCLUSIONS: Two-thirds of Singaporean adults with visually significant cataract were previously undiagnosed. Half of these cases had bilateral visual impairment and substantially reduced quality of life. Public health strategies targeting elderly patients, such as regular screening for visual impairment and timely referral to ophthalmologists in order to prevent progression to bilateral visual impairment when visual function is compromised are warranted.
dc.languageEnglish
dc.publisherPUBLIC LIBRARY SCIENCE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titlePrevalence, Risk Factors, and Impact of Undiagnosed Visually Significant Cataract: The Singapore Epidemiology of Eye Diseases Study
dc.typeJournal Article
dc.identifier.doi10.1371/journal.pone.0170804
melbourne.affiliation.departmentOphthalmology (Eye & Ear Hospital)
melbourne.source.titlePLoS One
melbourne.source.volume12
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1184097
melbourne.contributor.authorLamoureux, Ecosse
melbourne.contributor.authorFENWICK, EVA
melbourne.contributor.authorWong, Tien
dc.identifier.eissn1932-6203
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record