Show simple item record

dc.contributor.authorShankar-Hari, M
dc.contributor.authorBertolini, G
dc.contributor.authorBrunkhorst, FM
dc.contributor.authorBellomo, R
dc.contributor.authorAnnane, D
dc.contributor.authorDeutschman, CS
dc.contributor.authorSinger, M
dc.date.accessioned2020-12-22T04:26:47Z
dc.date.available2020-12-22T04:26:47Z
dc.date.issued2015-12-25
dc.identifierpii: 10.1186/s13054-015-1164-6
dc.identifier.citationShankar-Hari, M., Bertolini, G., Brunkhorst, F. M., Bellomo, R., Annane, D., Deutschman, C. S. & Singer, M. (2015). Judging quality of current septic shock definitions and criteria. CRITICAL CARE, 19 (1), https://doi.org/10.1186/s13054-015-1164-6.
dc.identifier.issn1364-8535
dc.identifier.urihttp://hdl.handle.net/11343/258070
dc.description.abstractSeptic shock definitions are being revisited. We assess the feasibility, reliability, and validity characteristics of the current definitions and criteria of septic shock. Septic shock is conceptualised as cardiovascular dysfunction, tissue perfusion and cellular abnormalities caused by infection. Currently, for feasibility, septic shock is identified at the bedside by using either hypotension or a proxy for tissue perfusion/cellular abnormalities (e.g., hyperlactatemia). We propose that concurrent presence of cardiovascular dysfunction and perfusion/cellular abnormalities could improve validity of septic shock diagnosis, as we are more likely to identify a patient population with all elements of the illness concept. This epidemiological refinement should not affect clinical care and may aid study design to identify illness-specific biomarkers and interventions.
dc.languageEnglish
dc.publisherBMC
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleJudging quality of current septic shock definitions and criteria
dc.typeJournal Article
dc.identifier.doi10.1186/s13054-015-1164-6
melbourne.affiliation.departmentCritical Care
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleCritical Care (UK)
melbourne.source.volume19
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1026961
melbourne.contributor.authorBellomo, Rinaldo
dc.identifier.eissn1466-609X
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record