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dc.contributor.authorTai, ELM
dc.contributor.authorLi, L-J
dc.contributor.authorWan-Hazabbah, WH
dc.contributor.authorWong, T-Y
dc.contributor.authorShatriah, I
dc.date.accessioned2020-12-22T04:37:30Z
dc.date.available2020-12-22T04:37:30Z
dc.date.issued2017-01-20
dc.identifierpii: PONE-D-16-34475
dc.identifier.citationTai, E. L. M., Li, L. -J., Wan-Hazabbah, W. H., Wong, T. -Y. & Shatriah, I. (2017). Effect of Axial Eye Length on Retinal Vessel Parameters in 6 to 12-Year-Old Malay Girls. PLOS ONE, 12 (1), https://doi.org/10.1371/journal.pone.0170014.
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/11343/258104
dc.description.abstractPURPOSE: Retinal vessel analysis is affected by both systemic and ocular factors. Malays are the major ethnicity in South East Asia. Data on the retinal microvasculature in Malays is limited, especially among children. We aim to evaluate the influence of ocular biometry on retinal vessel parameters in young Malay girls. METHODS: This was a cross-sectional, hospital-based study involving 86 Malay girls aged 6 to 12 years old in Hospital Universiti Sains Malaysia from 2015-2016. Ocular examination, refraction, biometry, retinal photography, and anthropometric measurements were performed. The central retinal arteriolar equivalent (CRAE), central retinal venular equivalent (CRVE) and overall fractal dimension (Df) were measured using validated computer-based methods (Singapore I vessel analyzer, SIVA version 3.0, Singapore). The associations of ocular biometry and CRAE, CRVE and Df were analyzed using multivariable analysis. RESULTS: The mean CRAE, CRVE and Df in Malay girls were 171.40 (14.40) um, 248.02 (16.95) um and 1.42 (0.05) respectively. Each 1 mm increase in axial length was associated with a reduction of 4.25 um in the CRAE (p = 0.03) and a reduction of 0.02 in the Df (p = 0.02), after adjustment for age, blood pressure and body mass index. No association was observed between axial length and CRVE. Anterior chamber depth and corneal curvature had no association with CRAE, CRVE or Df. CONCLUSION: Axial length affects retinal vessel measurements. Narrower retinal arterioles and reduced retinal fractal dimension were observed in Malay girls with longer axial lengths.
dc.languageEnglish
dc.publisherPUBLIC LIBRARY SCIENCE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleEffect of Axial Eye Length on Retinal Vessel Parameters in 6 to 12-Year-Old Malay Girls
dc.typeJournal Article
dc.identifier.doi10.1371/journal.pone.0170014
melbourne.affiliation.departmentOphthalmology (Eye & Ear Hospital)
melbourne.source.titlePLoS One
melbourne.source.volume12
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1184810
melbourne.contributor.authorWong, Tien
dc.identifier.eissn1932-6203
melbourne.accessrightsOpen Access


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