Show simple item record

dc.contributor.authorTrijatmiko, KR
dc.contributor.authorDuenas, C
dc.contributor.authorTsakirpaloglou, N
dc.contributor.authorTorrizo, L
dc.contributor.authorArines, FM
dc.contributor.authorAdeva, C
dc.contributor.authorBalindong, J
dc.contributor.authorOliva, N
dc.contributor.authorSapasap, MV
dc.contributor.authorBorrero, J
dc.contributor.authorRey, J
dc.contributor.authorFrancisco, P
dc.contributor.authorNelson, A
dc.contributor.authorNakanishi, H
dc.contributor.authorLombi, E
dc.contributor.authorTako, E
dc.contributor.authorGlahn, RP
dc.contributor.authorStangoulis, J
dc.contributor.authorChadha-Mohanty, P
dc.contributor.authorJohnson, AAT
dc.contributor.authorTohme, J
dc.contributor.authorBarry, G
dc.contributor.authorSlamet-Loedin, IH
dc.date.accessioned2020-12-22T04:52:07Z
dc.date.available2020-12-22T04:52:07Z
dc.date.issued2016-01-25
dc.identifierpii: srep19792
dc.identifier.citationTrijatmiko, K. R., Duenas, C., Tsakirpaloglou, N., Torrizo, L., Arines, F. M., Adeva, C., Balindong, J., Oliva, N., Sapasap, M. V., Borrero, J., Rey, J., Francisco, P., Nelson, A., Nakanishi, H., Lombi, E., Tako, E., Glahn, R. P., Stangoulis, J., Chadha-Mohanty, P. ,... Slamet-Loedin, I. H. (2016). Biofortified indica rice attains iron and zinc nutrition dietary targets in the field. SCIENTIFIC REPORTS, 6 (1), https://doi.org/10.1038/srep19792.
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/11343/258158
dc.description.abstractMore than two billion people are micronutrient deficient. Polished grains of popular rice varieties have concentration of approximately 2 μg g(-1) iron (Fe) and 16 μg g(-1) zinc (Zn). The HarvestPlus breeding programs for biofortified rice target 13 μg g(-1) Fe and 28 μg g(-1) Zn to reach approximately 30% of the estimated average requirement (EAR). Reports on engineering Fe content in rice have shown an increase up to 18 μg g(-1) in glasshouse settings; in contrast, under field conditions, 4 μg g(-1) was the highest reported concentration. Here, we report on selected transgenic events, field evaluated in two countries, showing 15 μg g(-1) Fe and 45.7 μg g(-1) Zn in polished grain. Rigorous selection was applied to 1,689 IR64 transgenic events for insert cleanliness and, trait and agronomic performances. Event NASFer-274 containing rice nicotianamine synthase (OsNAS2) and soybean ferritin (SferH-1) genes showed a single locus insertion without a yield penalty or altered grain quality. Endosperm Fe and Zn enrichment was visualized by X-ray fluorescence imaging. The Caco-2 cell assay indicated that Fe is bioavailable. No harmful heavy metals were detected in the grain. The trait remained stable in different genotype backgrounds.
dc.languageEnglish
dc.publisherNATURE PUBLISHING GROUP
dc.titleBiofortified indica rice attains iron and zinc nutrition dietary targets in the field
dc.typeJournal Article
dc.identifier.doi10.1038/srep19792
melbourne.affiliation.departmentSchool of BioSciences
melbourne.source.titleScientific Reports
melbourne.source.volume6
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1031032
melbourne.contributor.authorJohnson, Alexander
dc.identifier.eissn2045-2322
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record