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dc.contributor.authorBoesmans, W
dc.contributor.authorHao, MM
dc.contributor.authorVanden Berghe, P
dc.date.accessioned2020-12-22T04:57:44Z
dc.date.available2020-12-22T04:57:44Z
dc.date.issued2015-07-01
dc.identifierpii: jnm15096
dc.identifier.citationBoesmans, W., Hao, M. M. & Vanden Berghe, P. (2015). Optical Tools to Investigate Cellular Activity in the Intestinal Wall. JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY, 21 (3), pp.337-351. https://doi.org/10.5056/jnm15096.
dc.identifier.issn2093-0879
dc.identifier.urihttp://hdl.handle.net/11343/258180
dc.description.abstractLive imaging has become an essential tool to investigate the coordinated activity and output of cellular networks. Within the last decade, 2 Nobel prizes have been awarded to recognize innovations in the field of imaging: one for the discovery, use, and optimization of the green fluorescent protein (2008) and the second for the development of super-resolved fluorescence microscopy (2014). New advances in both optogenetics and microscopy now enable researchers to record and manipulate ac-tivity from specific populations of cells with better contrast and resolution, at higher speeds, and deeper into live tissues. In this review, we will discuss some of the recent developments in microscope technology and in the synthesis of fluorescent probes, both synthetic and genetically encoded. We focus on how live imaging of cellular physiology has progressed our under-standing of the control of gastrointestinal motility, and we discuss the hurdles to overcome in order to apply the novel tools in the field of neurogastroenterology and motility.
dc.languageEnglish
dc.publisherKOREAN SOC NEUROGASTROENTEROLOGY & MOTILITY
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.titleOptical Tools to Investigate Cellular Activity in the Intestinal Wall
dc.typeJournal Article
dc.identifier.doi10.5056/jnm15096
melbourne.affiliation.departmentAnatomy and Neuroscience
melbourne.source.titleJournal of Neurogastroenterology and Motility
melbourne.source.volume21
melbourne.source.issue3
melbourne.source.pages337-351
melbourne.identifier.nhmrc1071153
dc.rights.licenseCC BY-NC
melbourne.elementsid1189436
melbourne.contributor.authorHao, Marlene
dc.identifier.eissn2093-0887
melbourne.identifier.fundernameidNHMRC, 1071153
melbourne.accessrightsOpen Access


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