Show simple item record

dc.contributor.authorOnofrillo, C
dc.contributor.authorGalbiati, A
dc.contributor.authorMontanaro, L
dc.contributor.authorDerenzini, M
dc.date.accessioned2020-12-22T05:04:14Z
dc.date.available2020-12-22T05:04:14Z
dc.date.issued2017-01-17
dc.identifierpii: 13833
dc.identifier.citationOnofrillo, C., Galbiati, A., Montanaro, L. & Derenzini, M. (2017). The pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition. ONCOTARGET, 8 (3), pp.4257-4267. https://doi.org/10.18632/oncotarget.13833.
dc.identifier.issn1949-2553
dc.identifier.urihttp://hdl.handle.net/11343/258203
dc.description.abstractPre-ribosomal complex RPL5/RPL11/5S rRNA (5S RNP) is considered the central MDM2 inhibitory complex that control p53 stabilization during ribosome biogenesis inhibition. Despite its role is well defined, the dynamic of 5S RNP assembly still requires further characterization. In the present work, we report that MDM2 inhibition is dependent by a pre-existing population of 5S rRNA.
dc.languageEnglish
dc.publisherIMPACT JOURNALS LLC
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleThe pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition
dc.typeJournal Article
dc.identifier.doi10.18632/oncotarget.13833
melbourne.affiliation.departmentSurgery (St Vincent's)
melbourne.source.titleOncotarget
melbourne.source.volume8
melbourne.source.issue3
melbourne.source.pages4257-4267
dc.rights.licenseCC BY
melbourne.elementsid1185746
melbourne.contributor.authorOnofrillo, Carmine
dc.identifier.eissn1949-2553
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record