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    Hybrid imaging is the future of molecular imaging.

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    11
    Author
    Hicks, R; Lau, E; Binns, D
    Date
    2007-07
    Source Title
    Biomedical Imaging and Intervention Journal: a multidisciplinary open access online journal
    Publisher
    Department of Biomedical Imaging, University of Malaya, Malaysia
    University of Melbourne Author/s
    Lau, Wing
    Affiliation
    Medicine and Radiology
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Hicks, R., Lau, E. & Binns, D. (2007). Hybrid imaging is the future of molecular imaging.. Biomed Imaging Interv J, 3 (3), pp.e49-. https://doi.org/10.2349/biij.3.3.e49.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/258344
    DOI
    10.2349/biij.3.3.e49
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097677
    Abstract
    Correlative imaging has long been used in clinical practice and particularly for the interpretation of nuclear medicine studies wherein detailed anatomical information is often lacking. Previously, side-by-side comparison or software co-registration techniques were applied but suffered from technical limitations related to the differing geometries of the imaging equipment, differences in the positioning of patients and displacement of mobile structures between studies. The development of the first hybrid PET and CT device struck a chord with the medical imaging community that is still ringing loudly throughout the world. So successful has been the concept of PET-CT that none of the major medical imaging manufacturers now offers stand-alone PET scanners. Following close behind this success, SPECT-CT devices have recently been adopted by the nuclear medicine community, already compelled by the benefits of hybrid imaging through their experience with PET-CT. Recent reports of adaptation of PET detectors to operate within the strong magnetic field of MRI scanners have generated further enthusiasm. Prototype PET-MRI devices are now in development. The complementary anatomical, functional and molecular information provided by these techniques can now be presented in an intuitive and aesthetically-pleasing format. This has made end-users more comfortable with the results of functional imaging techniques than when the same information is presented independently. Despite the primacy of anatomical imaging for locoregional disease definition, the molecular characterisation available from PET and SPECT offers unique complementary information for cancer evaluation. A new era of cancer imaging, when hybrid imaging will be the primary diagnostic tool, is approaching.

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