Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon

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    Author
    Crabb, BS; de Koning-Ward, TF; Gilson, PR
    Date
    2011-03-31
    Source Title
    BMC Biology
    Publisher
    BIOMED CENTRAL LTD
    University of Melbourne Author/s
    Crabb, Brendan
    Affiliation
    Microbiology and Immunology
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    Document Type
    Journal Article
    Citations
    Crabb, B. S., de Koning-Ward, T. F. & Gilson, P. R. (2011). Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon. BMC BIOLOGY, 9 (1), https://doi.org/10.1186/1741-7007-9-21.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/258427
    DOI
    10.1186/1741-7007-9-21
    Abstract
    The ability to analyze gene function in malaria-causing Plasmodium parasites has received a boost with a recent paper in BMC Genomics that describes a genome-wide mutagenesis system in the rodent malaria species Plasmodium berghei using the transposon piggyBac. This advance holds promise for identifying and validating new targets for intervention against malaria. But further improvements are still needed for the full power of genome-wide molecular genetic screens to be utilized in this organism.See research article: http://www.biomedcentral.com/1471-2164/12/155.

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