Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon
AuthorCrabb, BS; de Koning-Ward, TF; Gilson, PR
Source TitleBMC Biology
PublisherBIOMED CENTRAL LTD
University of Melbourne Author/sCrabb, Brendan
AffiliationMicrobiology and Immunology
Document TypeJournal Article
CitationsCrabb, B. S., de Koning-Ward, T. F. & Gilson, P. R. (2011). Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon. BMC BIOLOGY, 9 (1), https://doi.org/10.1186/1741-7007-9-21.
Access StatusOpen Access
The ability to analyze gene function in malaria-causing Plasmodium parasites has received a boost with a recent paper in BMC Genomics that describes a genome-wide mutagenesis system in the rodent malaria species Plasmodium berghei using the transposon piggyBac. This advance holds promise for identifying and validating new targets for intervention against malaria. But further improvements are still needed for the full power of genome-wide molecular genetic screens to be utilized in this organism.See research article: http://www.biomedcentral.com/1471-2164/12/155.
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