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dc.contributor.authorLindqvist, LM
dc.contributor.authorSimon, AK
dc.contributor.authorBaehrecke, EH
dc.date.accessioned2021-02-03T23:38:09Z
dc.date.available2021-02-03T23:38:09Z
dc.date.issued2015-01-01
dc.identifier.citationLindqvist, L. M., Simon, A. K. & Baehrecke, E. H. (2015). Current questions and possible controversies in autophagy. CELL DEATH DISCOVERY, 1 (1), https://doi.org/10.1038/cddiscovery.2015.36.
dc.identifier.issn2058-7716
dc.identifier.urihttp://hdl.handle.net/11343/258935
dc.description.abstractInterest in autophagy has exploded over the last decade, with publications highlighting crosstalk with several other cellular processes including secretion, endocytosis, and cell suicide pathways including apoptosis. Autophagy proteins have also been implicated in other cellular processes independently of their roles in autophagy, creating complexities in the interpretation of autophagy (Atg) mutant gene data. Interestingly, this self-eating process is a survival mechanism that can also promote cell death, but when and how autophagy may 'switch' its function is still under debate. Indeed, there are currently many models of how autophagy actually influences cell death. In this review, we highlight some outstanding questions and possible controversies in the autophagy field.
dc.languageEnglish
dc.publisherNATURE PUBLISHING GROUP
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleCurrent questions and possible controversies in autophagy
dc.typeJournal Article
dc.identifier.doi10.1038/cddiscovery.2015.36
melbourne.affiliation.departmentMedical Biology (W.E.H.I.)
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleCell Death Discovery
melbourne.source.volume1
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1043072
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679147
melbourne.contributor.authorLindqvist, Lisa
dc.identifier.eissn2058-7716
melbourne.accessrightsOpen Access


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