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    Prevalence and Determinants of Suboptimal Vitamin D Levels in a Multiethnic Asian Population

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    23
    Author
    Man, REK; Li, L-J; Cheng, C-Y; Wong, TY; Lamoureux, E; Sabanayagam, C
    Date
    2017-03-01
    Source Title
    Nutrients
    Publisher
    MDPI
    University of Melbourne Author/s
    Lamoureux, Ecosse; Wong, Tien
    Affiliation
    Ophthalmology (Eye & Ear Hospital)
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Man, R. E. K., Li, L. -J., Cheng, C. -Y., Wong, T. Y., Lamoureux, E. & Sabanayagam, C. (2017). Prevalence and Determinants of Suboptimal Vitamin D Levels in a Multiethnic Asian Population. NUTRIENTS, 9 (3), https://doi.org/10.3390/nu9030313.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/259014
    DOI
    10.3390/nu9030313
    Abstract
    This population-based cross-sectional study examined the prevalence and risk factors of suboptimal vitamin D levels (assessed using circulating 25-hydroxycholecalciferol (25(OH)D)) in a multi-ethnic sample of Asian adults. Plasma 25(OH)D concentration of 1139 Chinese, Malay and Indians (40-80 years) were stratified into normal (≥30 ng/mL), and suboptimal (including insufficiency and deficiency, <30 ng/mL) based on the 2011 Endocrine Society Clinical Practice Guidelines. Logistic regression models were used to assess the associations of demographic, lifestyle and clinical risk factors with the outcome. Of the 1139 participants, 25(OH)D concentration was suboptimal in 76.1%. In multivariable models, age ≤65 years (compared to age >65 years), Malay and Indian ethnicities (compared to Chinese ethnicity), and higher body mass index, HbA1c, education and income levels were associated with suboptimal 25(OH)D concentration (p < 0.05). In a population-based sample of Asian adults, approximately 75% had suboptimal 25(OH)D concentration. Targeted interventions and stricter reinforcements of existing guidelines for vitamin D supplementation are needed for groups at risk of vitamin D insufficiency/deficiency.

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