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    Detecting functional decline from normal aging to dementia: Development and validation of a short version of the Amsterdam IADL Questionnaire.

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    24
    Author
    Jutten, RJ; Peeters, CFW; Leijdesdorff, SMJ; Visser, PJ; Maier, AB; Terwee, CB; Scheltens, P; Sikkes, SAM
    Date
    2017
    Source Title
    Alzheimer's & dementia (Amsterdam, Netherlands)
    Publisher
    Wiley
    University of Melbourne Author/s
    Maier, Andrea
    Affiliation
    Medicine and Radiology
    Metadata
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    Document Type
    Journal Article
    Citations
    Jutten, R. J., Peeters, C. F. W., Leijdesdorff, S. M. J., Visser, P. J., Maier, A. B., Terwee, C. B., Scheltens, P. & Sikkes, S. A. M. (2017). Detecting functional decline from normal aging to dementia: Development and validation of a short version of the Amsterdam IADL Questionnaire.. Alzheimers Dement (Amst), 8 (1), pp.26-35. https://doi.org/10.1016/j.dadm.2017.03.002.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/259220
    DOI
    10.1016/j.dadm.2017.03.002
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403784
    Abstract
    INTRODUCTION: Detecting functional decline from normal aging to dementia is relevant for diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A-IADL-Q) was developed: a 70-item proxy-based tool with good psychometric properties. We aimed to design a short version while preserving its psychometric quality. METHODS: Study partners of subjects (n = 1355), ranging from cognitively normal to dementia subjects, completed the original A-IADL-Q. We selected the short version items using a stepwise procedure combining missing data, Item Response Theory, and input from respondents and experts. We investigated internal consistency of the short version and concordance with the original version. To assess its construct validity, we additionally investigated concordance between the short version and the Mini-Mental State Examination (MMSE) and Disability Assessment for Dementia (DAD). Finally, we investigated differences in instrumental activities of daily living (IADL) scores between diagnostic groups across the dementia spectrum. RESULTS: We selected 30 items covering the entire spectrum of IADL functioning. Internal consistency (0.98) and concordance with the original version (0.97) were very high. Concordance with the MMSE (0.72) and DAD (0.87) scores was high. IADL impairment scores increased across the spectrum from normal cognition to dementia. DISCUSSION: The A-IADL-Q short version (A-IADL-Q-SV) consists of 30 items and has maintained the psychometric quality of the original A-IADL-Q. As such, the A-IADL-Q-SV is a concise measure of functional decline.

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