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dc.contributor.authorMeikle, P
dc.contributor.authorLow, H
dc.contributor.authorChurchill, MJ
dc.contributor.authorBukrinsky, M
dc.contributor.authorSviridov, D
dc.date.accessioned2021-02-04T00:56:08Z
dc.date.available2021-02-04T00:56:08Z
dc.date.issued2016-03-01
dc.identifierpii: S2352-3409(15)00364-9
dc.identifier.citationMeikle, P., Low, H., Churchill, M. J., Bukrinsky, M. & Sviridov, D. (2016). Lipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain. DATA IN BRIEF, 6, pp.168-175. https://doi.org/10.1016/j.dib.2015.11.067.
dc.identifier.issn2352-3409
dc.identifier.urihttp://hdl.handle.net/11343/259227
dc.description.abstractPrevious in vitro and in vivo studies demonstrated that HIV protein nef plays a key role in impairing cellular and systemic cholesterol metabolism in HIV disease, but clinical support for these findings is lacking. Here we present the data of comparative lipidomic analysis (330 lipid species) of plasma samples from HIV-negative subjects, patients infected with WT HIV-1 strain and patients infected with nef-deficient strain of HIV-1. We determine which effects of HIV on plasma lipidome are explained by the presence of nef. The data can be used to evaluate cardiovascular risk in HIV disease and to assess the role of nef in HIV-induced disturbances in systemic lipid metabolism. The full impact of nef deficiency on lipid and lipoprotein metabolism in HIV-infected patients is presented in the accompanying study "Lipid Metabolism in Patients Infected with Nef-deficient HIV-1 Strain" [1].
dc.languageEnglish
dc.publisherELSEVIER SCIENCE BV
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleLipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain
dc.typeJournal Article
dc.identifier.doi10.1016/j.dib.2015.11.067
melbourne.affiliation.departmentBio21
melbourne.affiliation.facultyAffiliate
melbourne.source.titleData in Brief
melbourne.source.volume6
melbourne.source.pages168-175
dc.rights.licenseCC BY
melbourne.elementsid1208086
melbourne.contributor.authorMeikle, Peter
dc.identifier.eissn2352-3409
melbourne.accessrightsOpen Access


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