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    Anticancer and Antitumor Potential of Fucoidan and Fucoxanthin, Two Main Metabolites Isolated from Brown Algae

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    Author
    Moghadamtousi, SZ; Karimian, H; Khanabdali, R; Razavi, M; Firoozinia, M; Zandi, K; Kadir, HA
    Date
    2014-01-01
    Source Title
    The Scientific World Journal
    Publisher
    HINDAWI LTD
    University of Melbourne Author/s
    Khanabdali, Ramin
    Affiliation
    Obstetrics and Gynaecology
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Moghadamtousi, S. Z., Karimian, H., Khanabdali, R., Razavi, M., Firoozinia, M., Zandi, K. & Kadir, H. A. (2014). Anticancer and Antitumor Potential of Fucoidan and Fucoxanthin, Two Main Metabolites Isolated from Brown Algae. SCIENTIFIC WORLD JOURNAL, 2014, https://doi.org/10.1155/2014/768323.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/259278
    DOI
    10.1155/2014/768323
    Abstract
    Seaweed is one of the largest producers of biomass in marine environment and is a rich arsenal of active metabolites and functional ingredients with valuable beneficial health effects. Being a staple part of Asian cuisine, investigations on the crude extracts of Phaeophyceae or brown algae revealed marked antitumor activity, eliciting a variety of research to determine the active ingredients involved in this potential. The sulfated polysaccharide of fucoidan and carotenoid of fucoxanthin were found to be the most important active metabolites of brown algae as potential chemotherapeutic or chemopreventive agents. This review strives to provide detailed account of all current knowledge on the anticancer and antitumor activity of fucoidan and fucoxanthin as the two major metabolites isolated from brown algae.

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