The life history of neochromosomes revealed

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    Author
    Papenfuss, AT; Thomas, DM
    Date
    2015-01-01
    Source Title
    Molecular & cellular oncology
    Publisher
    TAYLOR & FRANCIS INC
    University of Melbourne Author/s
    Papenfuss, Anthony; Thomas, David
    Affiliation
    Medical Biology (W.E.H.I.)
    Sir Peter MacCallum Department of Oncology
    Metadata
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    Document Type
    Journal Article
    Citations
    Papenfuss, A. T. & Thomas, D. M. (2015). The life history of neochromosomes revealed. MOLECULAR & CELLULAR ONCOLOGY, 2 (4), https://doi.org/10.1080/23723556.2014.1000698.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/259332
    DOI
    10.1080/23723556.2014.1000698
    Abstract
    Neochromosomes are a little-studied class of chromosome-scale mutations that drive some cancers. By sequencing isolated neochromosomes from liposarcomas, we recently defined their structure at single-nucleotide resolution and proposed a model for their life history. Here, we summarize that work, highlighting significant aspects and providing historical context and insight into the discovery process.

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