University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Clinical Pathology
  • Clinical Pathology - Research Publications
  • View Item
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Clinical Pathology
  • Clinical Pathology - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    Quality assurance for clinical trials.

    Thumbnail
    Download
    Published version (642.5Kb)

    Citations
    Scopus
    Altmetric
    23
    Author
    Ibbott, GS; Haworth, A; Followill, DS
    Date
    2013-12-19
    Source Title
    Frontiers in Oncology
    Publisher
    Frontiers Media SA
    University of Melbourne Author/s
    Haworth, Annette
    Affiliation
    Clinical Pathology
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Ibbott, G. S., Haworth, A. & Followill, D. S. (2013). Quality assurance for clinical trials.. Front Oncol, 3, pp.311-. https://doi.org/10.3389/fonc.2013.00311.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/259393
    DOI
    10.3389/fonc.2013.00311
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867736
    Abstract
    Cooperative groups, of which the Radiation Therapy Oncology Group is one example, conduct national clinical trials that often involve the use of radiation therapy. In preparation for such a trial, the cooperative group prepares a protocol to define the goals of the trial, the rationale for its design, and the details of the treatment procedure to be followed. The Radiological Physics Center (RPC) is one of several quality assurance (QA) offices that is charged with assuring that participating institutions deliver doses that are clinically consistent and comparable. The RPC does this by conducting a variety of independent audits and credentialing processes. The RPC has compiled data showing that credentialing can help institutions comply with the requirements of a cooperative group clinical protocol. Phantom irradiations have been demonstrated to exercise an institution's procedures for planning and delivering advanced external beam techniques (1-3). Similarly, RPC data indicate that a rapid review of patient treatment records or planning procedures can improve compliance with clinical trials (4). The experiences of the RPC are presented as examples of the contributions that a national clinical trials QA center can make to cooperative group trials. These experiences illustrate the critical need for comprehensive QA to assure that clinical trials are successful and cost-effective. The RPC is supported by grants CA 10953 and CA 81647 from the National Cancer Institute, NIH, DHHS.

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [52609]
    • Clinical Pathology - Research Publications [620]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors