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dc.contributor.authorZimmermann, P
dc.contributor.authorBerlinger, L
dc.contributor.authorLiniger, B
dc.contributor.authorGrunt, S
dc.contributor.authorAgyeman, P
dc.contributor.authorRitz, N
dc.date.accessioned2021-02-04T02:06:38Z
dc.date.available2021-02-04T02:06:38Z
dc.date.issued2012-08-28
dc.identifierpii: 1471-2334-12-201
dc.identifier.citationZimmermann, P., Berlinger, L., Liniger, B., Grunt, S., Agyeman, P. & Ritz, N. (2012). Actinobaculum schaalii an emerging pediatric pathogen?. BMC INFECTIOUS DISEASES, 12 (1), https://doi.org/10.1186/1471-2334-12-201.
dc.identifier.issn1471-2334
dc.identifier.urihttp://hdl.handle.net/11343/259575
dc.description.abstractBACKGROUND: Actinobaculum schaalii was first described as a causative agent for human infection in 1997. Since then it has mainly been reported causing urinary tract infections (UTI) in elderly individuals with underlying urological diseases. Isolation and identification is challenging and often needs molecular techniques. A. schaalii is increasingly reported as a cause of infection in humans, however data in children is very limited. CASE PRESENTATION: We present the case of an 8-month-old Caucasian boy suffering from myelomeningocele and neurogenic bladder who presented with a UTI. An ultrasound of the urinary tract was unremarkable. Urinalysis and microscopy showed an elevated leukocyte esterase test, pyuria and a high number of bacteria. Empiric treatment with oral co-trimoxazole was started.Growth of small colonies of Gram-positive rods was observed after 48 h. Sequencing of the 16S rRNA gene confirmed an A. schaalii infection 9 days later. Treatment was changed to oral amoxicillin for 14 days. On follow-up urinalysis was normal and urine cultures were negative. CONCLUSIONS: A.schaalii is an emerging pathogen in adults and children. Colonization and subsequent infection seem to be influenced by the age of the patient. In young children with high suspicion of UTI who use diapers or in children who have known abnormalities of their urogenital tract, infection with A. schaalii should be considered and empiric antimicrobial therapy chosen accordingly.
dc.languageEnglish
dc.publisherBMC
dc.titleActinobaculum schaalii an emerging pediatric pathogen?
dc.typeJournal Article
dc.identifier.doi10.1186/1471-2334-12-201
melbourne.affiliation.departmentPaediatrics (RCH)
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleBMC Infectious Diseases
melbourne.source.volume12
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1216454
melbourne.contributor.authorZimmermann, Petra
melbourne.contributor.authorRitz, Nicole
dc.identifier.eissn1471-2334
melbourne.accessrightsOpen Access


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