University Library
  • Login
A gateway to Melbourne's research publications
Minerva Access is the University's Institutional Repository. It aims to collect, preserve, and showcase the intellectual output of staff and students of the University of Melbourne for a global audience.
View Item 
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Paediatrics (RCH)
  • Paediatrics (RCH) - Research Publications
  • View Item
  • Minerva Access
  • Medicine, Dentistry & Health Sciences
  • Melbourne Medical School
  • Paediatrics (RCH)
  • Paediatrics (RCH) - Research Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

    Depression and Anxiety Outcomes Associated with Failed Assisted Reproductive Technologies: A Systematic Review and Meta-Analysis

    Thumbnail
    Download
    Published version (2.209Mb)

    Citations
    Scopus
    Altmetric
    22
    Author
    Milazzo, A; Mnatzaganian, G; Elshaug, AG; Hemphill, SA; Hiller, JE
    Date
    2016-11-11
    Source Title
    PLoS One
    Publisher
    PUBLIC LIBRARY SCIENCE
    University of Melbourne Author/s
    Hemphill, Sheryl; Elshaug, Adam
    Affiliation
    Paediatrics (RCH)
    Melbourne School of Population and Global Health
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Milazzo, A., Mnatzaganian, G., Elshaug, A. G., Hemphill, S. A. & Hiller, J. E. (2016). Depression and Anxiety Outcomes Associated with Failed Assisted Reproductive Technologies: A Systematic Review and Meta-Analysis. PLOS ONE, 11 (11), https://doi.org/10.1371/journal.pone.0165805.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/259656
    DOI
    10.1371/journal.pone.0165805
    Abstract
    OBJECTIVE: Our study examined the psychological outcomes associated with failed ART treatment outcomes in men and women. SEARCH STRATEGY: A systematic search for studies published between January 1980 and August 2015 was performed across seven electronic databases. INCLUSION CRITERIA: Studies were included if they contained data on psychosocial outcomes taken pre and post ART treatment. DATA EXTRACTION AND SYNTHESIS: A standardised form was used to extract data and was verified by two independent reviewers. Studies were meta-analysed to determine the association of depression and anxiety with ART treatment outcomes. Narrative synthesis identified factors to explain variations in the size and directions of effects and relationships explored within and between the studies. MAIN RESULTS: Both depression and anxiety increased after a ART treatment failure with an overall pooled standardised mean difference (SMD) of 0.41 (95% CI: 0.27, 0.55) for depression and 0.21 (95% CI: 0.13, 0.29) for anxiety. In contrast, depression decreased after a successful treatment, SMD of -0.24 (95% CI: -0.37,-0.11). Both depression and anxiety decreased as time passed from ART procedure. Nonetheless, these remained higher than baseline measures in the group with the failed outcome even six months after the procedure. Studies included in the narrative synthesis also confirmed an association with negative psychological outcomes in relation to marital satisfaction and general well-being following treatment failure. CONCLUSION: Linking ART failure and psychosocial outcomes may elucidate the experience of treatment subgroups, influence deliberations around recommendations for resource allocation and health policy and guide patient and clinician decision making.

    Export Reference in RIS Format     

    Endnote

    • Click on "Export Reference in RIS Format" and choose "open with... Endnote".

    Refworks

    • Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References


    Collections
    • Minerva Elements Records [52369]
    • Melbourne School of Population and Global Health - Research Publications [5312]
    • Paediatrics (RCH) - Research Publications [2382]
    Minerva AccessDepositing Your Work (for University of Melbourne Staff and Students)NewsFAQs

    BrowseCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    My AccountLoginRegister
    StatisticsMost Popular ItemsStatistics by CountryMost Popular Authors