An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment

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    Author
    Xia, S; Zhang, X; Zheng, S; Khanabdali, R; Kalionis, B; Wu, J; Wan, W; Tai, X
    Date
    2016-01-01
    Source Title
    Journal of Immunology Research
    Publisher
    HINDAWI LTD
    University of Melbourne Author/s
    Kalionis, Bill; Khanabdali, Ramin
    Affiliation
    Obstetrics and Gynaecology
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    Document Type
    Journal Article
    Citations
    Xia, S., Zhang, X., Zheng, S., Khanabdali, R., Kalionis, B., Wu, J., Wan, W. & Tai, X. (2016). An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment. JOURNAL OF IMMUNOLOGY RESEARCH, 2016, https://doi.org/10.1155/2016/8426874.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/260072
    DOI
    10.1155/2016/8426874
    Abstract
    Inflamm-aging is a challenging and promising new branch of aging-related research fields that includes areas such as immunosenescence. Increasing evidence indicates that inflamm-aging is intensively associated with many aging diseases, such as Alzheimer's disease, atherosclerosis, heart disease, type II diabetes, and cancer. Mounting studies have focused on the role of inflamm-aging in disease progression and many advances have been made in the last decade. However, the underlying mechanisms by which inflamm-aging affects pathological changes and disease development are still unclear. Here, we review studies of inflamm-aging that explore the concept, pathological features, mechanisms, intervention, and the therapeutic strategies of inflamm-aging in disease progression.

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